Ciaula AD, Portincasa P, Terlizzi LD, Paternostro D, Palasciano G. Ultrasonographic study of postcibal gastro-esophageal reflux and gastric emptying in infants with recurrent respiratory disease. World J Gastroenterol 2005; 11(46): 7296-7301 [PMID: 16437631 DOI: 10.3748/wjg.v11.i46.7296]
Corresponding Author of This Article
Agostino Di Ciaula, MD, Division of Internal Medicine, P.O. Bisceglie, 70052 Bisceglie (BA), Italy. agostinodiciaula@tiscali.it
Article-Type of This Article
Clinical Research
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Dec 14, 2005; 11(46): 7296-7301 Published online Dec 14, 2005. doi: 10.3748/wjg.v11.i46.7296
Table 1 Characteristics of enrolled subjects
Patients
Controls
P
N
35
31
Age (mo)
5.6±2.9
4.5±3.6
NS
Weight (kg)
7.4±2.0
6.7±1.7
NS
Height (m)
0.7±0.07
0.6±0.01
NS
Table 2 Ultrasonographic characteristics of gastro-esophageal reflux in infants with recurrent respiratory diseases and in healthy controls
Patients
Controls
P
Number of reflux episodes
10 (2-21)
3 (1-9)
<0.01
Reflux frequency (reflux episodes/min)
0.5 (0.1-1.05)
0.15 (0.05-0.45)
<0.01
Maximal esophageal lumen enlargement (mm)
5 (1-17)
1.5 (1-9)
<0.01
Duration of the longest reflux episode (s)
11 (2-18)
4 (2-12)
<0.01
Table 3 Ultrasonographic characteristics of gastro-esophageal reflux in patients with recurrent respiratory diseases in two age groups
0-6 mo
7-12 mo
P
Number of reflux episodes
9.5 (3-21)
11 (2-18)
NS
Reflux frequency (reflux episodes/min)
0.5 (0.15-1.05)
0.6 (0.1-0.9)
NS
Maximal esophageal lumen enlargement (mm)
5.5 (1-17)
4 (1.6-11.5)
NS
Duration of the longest reflux episode (s)
11 (2-17)
7 (4-18)
NS
Table 4 Ultrasonographic characteristics of gastro-esophageal reflux in patients with or without symptomatic reflux episodes
Withsymptomaticreflux
Withoutsymptomaticreflux
P
Subjects
20
15
Number of reflux episodes
11.5 (4-21)
7 (2-18)
<0.02
Reflux frequency (reflux episodes/min)
0.58 (0.2-1.05)
0.4 (0.1-0.9)
<0.05
Maximal esophageal lumen enlargement (mm)
5.5 (1.7-13.5)
3.0 (1-17)
NS
Duration of the longest reflux episode (s)
11 (6-18)
8 (2-17)
NS
Table 5 Ultrasonographic characteristics of gastro-esophageal reflux in patients with recurrent episodes of bronchitis (group A), chronic cough (group B), and in healthy controls
Table 6 Ultrasonographic characteristics of gastro-esophageal reflux in infants with recurrent respiratory diseases, with or without daily regurgitation
With dailyregurgitation
Without dailyregurgitation
P
Subjects
20 (57%)
15 (43%)
NS
Number of reflux episodes (N)
10.5 (5-21)
8 (2-18)
<0.03
Reflux frequency (N/min)
0.5 (0.25-1.05)
0.4 (0.1-0.9)
<0.03
Maximal esophageal lumen enlargement (mm)
5 (1.5-17)
4 (1.0-11.5)
NS
Duration of the longest reflux episode (s)
11.5 (3-17)
7 (2-18)
<0.01
Citation: Ciaula AD, Portincasa P, Terlizzi LD, Paternostro D, Palasciano G. Ultrasonographic study of postcibal gastro-esophageal reflux and gastric emptying in infants with recurrent respiratory disease. World J Gastroenterol 2005; 11(46): 7296-7301