Rapid Communication
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 7, 2005; 11(45): 7159-7164
Published online Dec 7, 2005. doi: 10.3748/wjg.v11.i45.7159
Table 1 Crude and age-adjusted odds ratios of baseline-associated factors of GSD among type 2 diabetics in Kinmen
GSD (yes vs no)
Male
Female
Crude OR (95%CI)Age-adjusted OR (95%CI)Crude OR (95%CI)Age-adjusted OR (95%CI)
Age (≥65 vs ＜65 yr)3.14(1.32-7.47)a--2.25(1.04-4.90)a--
Type 2 diabetes (known vs new cases)0.90(0.34-2.39)0.87(0.32-2.34)1.44(0.68-3.02)1.46(0.68-3.13)
FPG (≥11.1 vs ＜11.1 mmol/L)2.12(0.70-6.37)1.95(0.64-5.94)1.24(0.50-3.07)1.49(0.59-3.79)
SBP (≥140 vs ＜140 mmHg)1.70(0.73-3.97)1.50(0.63-3.56)2.59(1.23-5.46)a1.99(0.92-4.31)
DBP (≥90 vs ＜90 mmHg)1.44(0.62-3.35)1.57(0.67-3.73)1.12(0.52-2.42)1.21(0.55-2.67)
Obesity (yes vs no)2.04(0.85-4.88)2.00(0.83-4.83)2.97(1.30-6.83)a2.88(1.24-6.70)a
Central obesity (yes vs no)2.76(1.13-6.77)a2.36(1.01-5.97)1.85(0.68-5.02)1.47(0.53-4.09)
Cholesterol (≥5.17 vs ＜5.17 mmol/L)1.02(0.19-1.91)0.88(0.18-1.09)0.92(0.45-1.88)0.85(0.41-1.77)
Triglyceride (≥2.24 vs ＜2.24 mmol/L)1.92(0.12-2.36)1.61(0.13-2.84)1.43(0.20-2.46)1.35(0.15-1.96)
BUN (≥7.14 vs ＜7.14 mmol/L)0.44(0.16-1.25)0.38(0.13-1.09)1.65(0.75-3.61)1.30(0.58-2.93)
Uric acid (high vs normal)0.30(0.09-1.06)0.29(0.08-1.03)1.61(0.77-3.38)1.12(0.51-2.48)
AST (≥40 vs ＜40 U/L)1.05(0.08-5.72)0.60(0.07-5.31)3.68(1.01-9.32)a3.93(1.04-10.89)a
ALT (≥40 vs ＜40 U/L)1.09(0.19-4.33)1.09(0.21-5.61)2.00(0.67-6.02)2.20(0.71-6.85)
Serum insulin (2ndvs 1st quartile)0.29(0.06-1.33)0.30(0.06-1.39)1.39(0.44-4.40)1.68(0.52-5.45)
(μU/mL) (3rdvs 1st quartile)0.61(0.19-2.00)0.56(0.17-1.86)2.05(0.71-5.88)2.20(0.75-6.45)
(4thvs 1st quartile)0.61(0.18-2.03)0.65(0.20-2.17)5.38(2.14-13.48)a5.32(2.08-13.64)a
Log HOMA IR (2ndvs 1st quartile)0.61(0.19-2.00)0.60(0.18-1.99)1.17(0.38-3.57)1.65(0.52-5.29)
(3rdvs 1st quartile)0.58(0.06-1.29)0.49(0.06-1.36)2.60(1.02-6.64)a2.66(1.02-6.94)a
(4thvs 1st quartile)0.63(0.19-2.08)0.60(0.18-2.01)2.60(1.01-6.66)a2.59(1.01-6.76)a
Log HOMA β-cell (2ndvs 1st quartile)1.16(0.35-3.80)1.27(0.38-4.25)0.35(0.08-1.55)0.45(0.10-2.03)
(3rdvs 1st quartile)0.52(0.11-2.43)0.51(0.11-2.39)0.16(0.02-1.23)0.17(0.02-1.35)
(4thvs 1st quartile)0.25(0.03-2.97)0.22(0.03-1.73)0.17(0.02-1.28)0.16(0.02-1.21)
aP＜0.05.
Table 2 Multiple logistic regression of association between baseline serum insulin, insulin resistance, β-cell dysfunction and GSD among type 2 diabetics in Kinmen
VariablesGSD (yes vs no)
Male
Female
OR(95%CI)POR(95%CI)P
for trend testfor trend test
Model I
Age (≥65 vs ＜65 years)1.04(1.00-1.09)-1.05(1.02-1.09)-
Obesity (yes vs no)---2.35(1.04-5.62)-
Central obesity(yes vs no)2.66(1.01-6.99)----
Serum insulin (μU/mL)
2ndvs 1st quartile0.39(0.08-1.99)1.47(0.44-4.87)
3rdvs 1st quartile0.52(0.14-1.95)0.512.01(0.68-5.96)
4thvs 1st quartile0.56(0.16-2.04)4.46(1.71-11.66)
Model II
Age (≥65 vs ＜65 years)1.04(1.02-1.09)-1.06(1.02-1.10)-
Obesity (yes vs no)---2.25(1.02-5.52)-
Central obesity(yes vs no)2.68(1.03-6.97)----
Log HOMA IR
2ndvs 1st quartile0.79(0.22-2.78)1.63(0.49-5.43)
3rdvs 1st quartile0.53(0.07-1.51)0.181.63(0.55-4.82)0.02
4thvs 1st quartile0.68(0.20-2.36)2.81(1.03-7.91)
Model III
Age (≥65 vs ＜65 years)1.05(1.00-1.10)-1.05(1.01-1.09)-
Obesity (yes vs no)---2.58(1.09-6.13)-
Central obesity(yes vs no)2.82(1.03-7.69)----
Log HOMA β-cell
2ndvs 1st quartile0.94(0.60-9.97)0.45(0.10-2.09)
3rdvs 1st quartile0.78(0.15-4.09)0.140.17(0.02-1.31)0.01
4thvs 1 quartile0.32(0.04-2.89)0.16(0.03-1.70)
Other independent variables controlled in model included age, type of cases, SBP, DBP, cholesterol, triglyceride, BUN, uric acid, AST, and ALT.