Basic Research
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 7, 2005; 11(41): 6459-6465
Published online Nov 7, 2005. doi: 10.3748/wjg.v11.i41.6459
Table 1 WBC and PMN cells count (/µL, mean±SD)
GroupWBC after 5 hWBC after 9 hPMN after 5 hPMN after 9 h
(/µL)(/µL)(/µL)(/µL)
Control5 120  ± 1 2205 597 ± 1 4471230 ± 4901 434 ± 569
AP2 204a± 705a4 225 ±583614a ± 229a1 286 ± 598
AP+MoAb3 942c± 493c4 037 ±1 7782 315c±850c1 120 ± 705
AP+LPS1 678  ± 2596 762c±580c1 047 ± 5605 146c±1 124c
AP+MoAb4 087  ± 2595 450 ± 5801 830 ± 5603 250 ± 1 124
+LPS
MoAb6 587±1 0033 887 ± 1 6122 200 ± 502990 ± 307
LPS3 771a±1 510a4 100 ± 1 8242 892a±1 372a2 959a±1 553a
Table 2 SH compound and MDA concentration within pancreatic homogenate (nmol/mg protein, mean±SD)
GroupSH after 5 hH after 9 hMDA after 5 hMDA after 9 h
Control60.3 ± 7.364.7 ± 8.30.21 ± 0.020.22 ± 0.03
AP40.2a ± 8.5a43.5a ± 4.3a0.38a ± 0.07a0.39a ± 0.03a
AP+MoAb40.0 ± 6.546.7 ± 1.40.25c ± 0.06c0.26c ± 0.03c
AP+LPS40.0±6.841.1 ± 8.20.39 ± 0.070.41 ± 0.1
AP+MoAb39.0 ± 6.740.4 ± 5.00.37 ± 0.080.35 ± 0.2
+LPS
MoAb63.4 ± 8.659.4 ± 9.00.2 ± 0.030.21 ± 0.04
LPS52.0 ± 9.148.6 ± 4.70.28 ± 0.040.35 ± 0.05
Table 3 Plasma α-amylase and lipase activity (U/L, mean ± SD)
GroupΑ-AmylaseΑ-AmylaseLipaseLipase
after 5 hafter 9 hafter 5 hafter 9 h
Control690 ± 120743 ± 1566 ± 88 ± 9
AP8 286a ± 143a5 908a ± 640a2 140a ± 1 123a929a ± 252a
AP+MoAb5 119 ± 2 4872 293c ± 1 739c1 704 ± 731342c ± 178c
AP+LPS9 310 ± 7 5524 001 ± 1 6382 573 ± 2 1331 257 ± 164
AP+MoAb12 699c ± 4 978c2 719c ± 634c3 470 ± 1 832305c ± 65c
+LPS
MoAb696 ± 151582 ± 27321 ± 128 ± 4
LPS584 ± 182332 ± 9311 ± 88 ± 4
Table 4 Plasma IL-6 concentration (pg/mL, mean ± SD)
GroupIL-6 after 5 hIL-6 after 9 h
AP0.6 ± 2.00.0 ± 0.0
AP+MoAb4.7 ± 7.00.0 ± 0.0
AP+LPS982.0c ± 749.0c10.0 ± 20.0
AP+MoAb+LPS1 561.0c ± 493.0c0.0 ± 0.0
Control0.2 ± 0.30.1 ± 0.3
MoAb0.0 ± 0.00.0 ± 0.0
LPS941.0a ± 756.0a2.0 ± 4.0
Table 5 Microscopic findings within the pancreatic gland (mean ± SD)
HouvsEdema
Vacuolization
Infiltration
Necrosis
59595959
Group 10.000.000.000.001.11.210.000.00
Control±0.00±0.00±0.00±0.00±0.9±1.03±0.00±0.00
Group 21.91a0.502.50a1.007.40a14.60a0.170.25
AP±0.90a±0.57±0.90a±1.41±5.29a±2.37a±0.38±0.50
Group 32.281.501.711.503.87c10.950.000.00
AP+MoAb CD11b±0.75±1.00±0.4 8±1.00±1.69c±0.92±0.00±0.00
Group 41.282.001.571.2510.9417.920.140.00
AP+LPS±1.25±1.15±1.39±1.25±3.02±5.98±0.37±0.00
Group 52.501.002.001.0010.4015.100.000.00
AP+MoAbCD11b +LPS±1.00±0.00±1.15±0.00±8.30±6.46±0.00±0.00
Group 60.250.000.000.000.800.250.000.00
Control+MoAb CD11b±0.50±0.00±0.00±0.00±1.04±0.30±0.00±0.00
Group 70.000.000.000.002.456.00a0.000.00
Control+LPS±0.00±0.00±0.00±0.00±2.75±4.11a±0.00±0.00