Qian HG, Jing-Shen, Ma H, Ma HC, Su YH, Hao CY, Xing BC, Huang XF, Shou CC. Preliminary study on proteomics of gastric carcinoma and its clinical significance. World J Gastroenterol 2005; 11(40): 6249-6253 [PMID: 16419150 DOI: 10.3748/wjg.v11.i40.6249]
Corresponding Author of This Article
Dr. Hong-gang Qian, Department of Surgery, Peking University School of Clinical Oncology and Beijing Cancer Hospital, 52 Fucheng lu, Haidian District, Beijing 100036, China. qianhg@sohu.com
Article-Type of This Article
Gastric Cancer
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Oct 28, 2005; 11(40): 6249-6253 Published online Oct 28, 2005. doi: 10.3748/wjg.v11.i40.6249
Table 1 Samples of control and gastric cancer staged by TNM classification
Training group
Test group
Total
Gastric cancer
30
40
70
Stage I
6
6
Stage II
4
5
Stage III
12
16
Stage IV
8
13
Control
30
30
60
Total
60
70
130
Table 2 Mass peaks found in the model group
M/Z
P
Mean-cancer
Mean-control
7 567
3.7E-09
9.92
2.14
15 117
1.024E-07
10.14
1.69
15 326
2.675E-07
2.57
0.6
15 847
2.86434E-05
7.08
2.32
5 252
7.42542E-05
1.59
4.24
2 675
0.000603611
1.16
2.29
5 546
0.000879454
2.09
3.97
7 934
0.001268535
8.04
3.25
4 524
0.001335592
2.63
1.66
5 340
0.001335592
14.9
27.46
8 052
0.001637839
3.8
1.86
4 177
0.002210593
2.8
6.73
3 995
0.005201923
1.35
1.97
6 982
0.007451088
2.78
1.78
4 714
0.008874709
3.1
2.08
3 245
0.009673852
1.49
2.26
Table 3 Statistical summary of the model (by BPS)
Group
Sensitivity (%)
Specificity (%)
Accuracy (%)
Training
96.7
96.7
96.7
Test
90
86.7
88.6
Table 4 Status of the miss-judged test samples
Sex
Age (yr)
Differentiation of tumorgy
TNM
Stage
1 Female
32
Poor
T4N1M1
IV
2 Male
58
Poor, partially with signet
ring cell
T3N2M0
III
3 Female
63
Poor
T4N2M1
IV
4 Female
50
Poor, partially with signet
ring cell
T4N1M0
III
Citation: Qian HG, Jing-Shen, Ma H, Ma HC, Su YH, Hao CY, Xing BC, Huang XF, Shou CC. Preliminary study on proteomics of gastric carcinoma and its clinical significance. World J Gastroenterol 2005; 11(40): 6249-6253