Zeng L, Cao J, Zhang X. Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract. World J Gastroenterol 2005; 11(39): 6202-6207 [PMID: 16273651 DOI: 10.3748/wjg.v11.i39.6202]
Corresponding Author of This Article
Dr. Jiang Cao, Clinical Research Institute, Sir Run Run Shaw Hospital, Zhejiang University, 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. caoj@zju.edu.cn
Article-Type of This Article
Brief Reports
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 4 Correlation between HAI-1 and SNC19/matriptase expression and clinicopathology in colorectal cancer tissues [M(QR)]
Patients
HAI-1
SNC19
HAI-1:SNC19
Age yr
<40 yr
3
0.004 (0.003)
0.005 (0.002)
0.778 (0.349)
40-60 yr
10
0.007 (0.102)
0.003 (0.003)
0.798 (1.096)
>60 yr
23
0.009 (0.104)
0.005 (0.005)
0.677 (0.459)
Unkown
1
Gender
Men
13
0.005 (0.109)
0.005 (0.006)
0.944 (0.728)
Women
24
0.009 (0.100)
0.005 (0.004)
0.667 (0.592)
Location
Cecum/ascending colon
9
0.009 (0.101)
0.005 (0.006)
0.660 (0.482)
Transverse colon
2
0.003 (0.003)
0.002 (0.002)
0.862 (0.377)
Descending/sigmoid colon
6
0.010 (0.004)
0.006 (0.002)
0.663 (0.715)
Rectum
19
0.005 (0.009)
0.004 (0.005)
0.778 (1.158)
Unknown
1
Tumor histology
Adenocarcinoma
32
0.005 (0.009)
0.004 (0.005)
0.734 (0.788)
Mucoid carcinoma
4
0.009 (0.012)
0.005 (0.004)
0.511 (0.194)
Poorly differentiated carcinoma
1
N factor
N0
18
0.010(0.015)
0.005(0.009)
1.470(0.699)
N1/N2
19
0.007(0.005)
0.005(0.004)
1.480(0.980)
Dukes’ stage
A
7
0.011(0.015)
0.004(0.008)
1.790(3.860)
B
10
0.010(0.016)
0.006(0.015)
1.290(1.243 )
C/D
20
0.006(0.006)
0.005(0.005)
1.385(0.955)
Histological grade
Well
8
0.005(0.010)
0.006(0.024)
0.891(1.482)
Moderately
24
0.009(0.009)
0.004(0.005)
1.485(1.250 )
Poorly
5
0.009(0.012)
0.005(0.005)
1.790(1.000)
Citation: Zeng L, Cao J, Zhang X. Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract. World J Gastroenterol 2005; 11(39): 6202-6207