Zhu X, Zhang SH, Zhang KH, Li BM, Chen J. Value of endoscopic methylene blue and Lugol's iodine double staining and detection of GST-Π and telomerase in the early diagnosis of esophageal carcinoma. World J Gastroenterol 2005; 11(39): 6090-6095 [PMID: 16273632 DOI: 10.3748/wjg.v11.i39.6090]
Corresponding Author of This Article
Dr. Xuan Zhu, Department of Gastroenterology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang 330006, Jiangxi Province, China. jyyfyzx@163.com
Article-Type of This Article
Esophageal Cancer
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 5 Telomerase activity expression in various histological mucosa of esophagus (n, %)
Histology
n
Telomerase activity expression
Positive numberof telomerase (%)
+
-
Low-grade dysplasia
17
2
15
2 (11.8)
Moderate-grade dysplasia
21
7
14
7 (33.3)
High-grade dysplasia
41
32
9
32 (78.0)
Table 6 Expressions of GST-Π and telomerase activity in esophageal carcinoma and premalignant lesions
Normal epithelium
Hyperplasia
Dysplasia
Carcinoma
GST- ϕ (+)
GST- ϕ (-)
GST- ϕ (+)
GST-Π (-)
GST-Π (+)
GST- ϕ (-)
GST-Π (+)
GST-Π (-)
TA (+)
0
2
0
1
36
5
43
6
TA (-)
3
48
2
18
13
25
3
3
Citation: Zhu X, Zhang SH, Zhang KH, Li BM, Chen J. Value of endoscopic methylene blue and Lugol's iodine double staining and detection of GST-Π and telomerase in the early diagnosis of esophageal carcinoma. World J Gastroenterol 2005; 11(39): 6090-6095