Esophageal Cancer
Copyright ©The Author(s) 2005.
World J Gastroenterol. Oct 21, 2005; 11(39): 6090-6095
Published online Oct 21, 2005. doi: 10.3748/wjg.v11.i39.6090
Table 1 Endoscopic MB and Lugol's iodine double staining (n, %)
HistologynAreas stained blue (%)Areas between both the colors (%)Areas stained brown (%)
Normal epithelium5349 (92.5)4 (7.5)0
Hyperplasia2113 (61.9)6 (28.6)2 (9.5)
Dysplasia7910 (12.6)45 (57.0)24 (30.4)
Low-grade177 (41.2)7 (41.2)3 (17.6)
Moderate-grade213 (14.3)13 (61.9)5 (29.4)
High-grade41025 (61.0)16 (39.0)
Carcinoma5509 (16.4)46 (83.6)
Carcinoma in situ101 (100)0
Squamous cell carcinoma5108 (15.7)43 (84.3)
Adenocarcinoma3003 (100)
Total208726472
Table 2 GST-Π protein expression in esophageal carcinogenesis (n, %)
HistologynGST-Π expression
Positiverate (%)
-+++++
Normal epithelium53503005.7
Hyperplasia21192009.51
Dysplasia79303412362.0b
Carcinoma5593013383.6b
Table 3 GST-Π protein expression in various histology mucosa of esophagus (n, %)
HistologynGST-Π expression
Positiverate (%)
-+++++
Low-grade dysplasia171151035.3
Moderate-grade dysplasia21983157.1
High-grade dysplasia4110218275.6
Table 4 Telomerase activity expression in esophageal carcinogenesis (n, %)
HistologynTelomerase activity expression
Positive numberof telomerase (%)
+-
Normal epithelium532512 (3.8)
Hyperplasia211201 (4.8)1
Dysplasia79412841 (51.9)a
Carcinoma5549649 (89.1)c
Table 5 Telomerase activity expression in various histological mucosa of esophagus (n, %)
HistologynTelomerase activity expression
Positive numberof telomerase (%)
+-
Low-grade dysplasia172152 (11.8)
Moderate-grade dysplasia217147 (33.3)
High-grade dysplasia4132932 (78.0)
Table 6 Expressions of GST-Π and telomerase activity in esophageal carcinoma and premalignant lesions
Normal epithelium
Hyperplasia
Dysplasia
Carcinoma
GST- ϕ (+)GST- ϕ (-)GST- ϕ (+)GST-Π (-)GST-Π (+)GST- ϕ (-)GST-Π (+)GST-Π (-)
TA (+)0201365436
TA (-)348218132533