Normal serum alanine aminotransferase activity in uncomplicated obesity

Table 1 Anthropometric and metabolic characteristics of uncomplicated obese subjects

	BMI <40(n=59)	BMI >40(n=46)	P
Age (yr)	36.4±9.2	32.8±8.5	NS
Women (n)	49	38	NS
FFM (kg)	57.9±7.4	56.3±7.35	NS
Fasting glucose (mmol/L)	4.69±0.47	4.77±0.44	NS
2 h OGTT glucose (mmol/L)	5.90±1.08	6.18±1	NS
Total cholesterol (mmol/L)	4.84±0.67	4.61±0.63	NS
HDL-C (mmol/L)	1.36±0.3	1.30±0.28	NS
LDL-C (mmol/L)	3.17±0.64	3.23±0.62	NS
Triglycerides (mmol/L)	0.98±0.34	1.02±0.34	NS
Systolic BP (kPa)	16.05±1.31±3.4129.8	16.05±1.38	NS
Diastolic BP (kPa)	10.13±1.11	10.26±1.10	NS
Fasting insulin (pmol/L)	95.4±55.8	139.2±70.8	<0.05
Leptin (μg/L)	27.4±16.4	45.5±17.9	<0.01
Leptin/BMI ratio	0.76±0.30	0.86±0.35	NS
Adiponectin (mg/L)	40.3±21.4	25.20±17.3	<0.05
ALT (U/L)	17.26±6.02	18.63±6.25	NS
AST (U/L)	24.65±9.82	29.46±10.82	NS
AST/ALT ratio	1.43±0.49	1.56±0.45	NS
γGT (U/L)	28.12±16.51	26.34±15.591

Data are expressed as mean±SD; SI units were used. BMI: body mass index; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; BP: blood pressure; FFM: free-fat mass; ALT: alanine aminotransferase; AST: aspartate aminotransferase; γGT: γ-glutamyltranspeptidase.