Comparison of a monoclonal antigen stool test (Hp StAR) with the 13C-urea breath test (UBT) in monitoring Helicobacter pylori eradication therapy

Table 1 UBT and Hp StAR results in study population. Biopsy-based tests were performed only in patients with discordant UBT and Hp StAR results

Pts	DOB(POS>5)	OD(POS>0.19)	Histology	Culture	RUT	Hp status
189 pts	0.01–2.53	0.03–0.17	np	np	np	NEG
Pt162	1.11	0.25	NEG	NEG	NEG	NEG
Pt177	0.74	0.26	NEG	NEG	NEG	NEG
Pt97	0.28	0.3	NEG	NEG	NEG	NEG
Pt98	1.52	0.33	NEG	NEG	NEG	NEG
Pt96	0.73	0.34	NEG	NEG	NEG	NEG
Pt179	0.11	0.29	POS	POS	NEG	POS
Pt223	0.31	0.3	POS	NEG	POS	POS
Pt201	1.07	0.34	POS	POS	NEG	POS
Pt72	3.56	0.61	NEG	POS	POS	POS
Pt47	4.24	0.23	POS	NEG	POS	POS
51 pts	6.81–86.15	0.23–2.93	np	np	np	POS

Table 2 Diagnostic accuracy of UBT and Hp StAR

	UBT	Hp StAR
Sensitivity	91.8 (87.4–91.8)	100 (95.2–100)
Sens=TP/(TP+FN)
Specificity	100 (98.6–100)	97.4 (96–97.4)
Spec=TN/(TN+FP)
Positive predictive value	100 (95.2–100)	91.8 (87.4–91.8)
+PV=TP/(TP+FP)
Negative predictive value	97.4 (96–97.4)	100 (98.6–100)
–PV=TN/(TN+FN)
Positive likelihood ratio	¥ (60.9–¥)	38.8 (23.2–38.8)
+LR=Sens/(100–Spec)
Negative likelihood ratio	8.2 (8.2–12.8)	0 (0–0.05)
–LR=(100–Sens)/Spec