Role of perioperative parenteral nutrition in severely malnourished patients with Crohn’s disease

Table 1 Clinical characteristics of two groups before parenteral nutrition

Group	Non-malnutrition group	Malnutrition group	P
Patients	16	16
Age (yr)	28 (20–73)	30 (18–71)	0.47
Sex (M/F)	9/7	10/6	0.6
Localization
Small bowel	5	6	0.59
Colon	5	3	0.28
Ileocolic	6	7	0.61
Medication
Corticosteroid	No	No
Sulfasalazine	7/16	6/16	0.61
Former body weight (%)	92.6±5.3	77.9±6.1	0.03

Table 2 Levels of immunoglobulin before and after parenteral nutrition (mean±SD)

Immunoglobulins	Normal value (mg/dL)	Non-malnutrition group		Malnutrition group
		Before PN	After PN	Before PN	After PN
IgA	203 ± 50	195 ± 42	218 ± 53	201 ± 38	215 ± 41
IgM	110 ± 35	133 ± 161	129 ± 13	139 ± 412	105 ± 293
IgG	1210 ± 300	1160 ± 280	1250 ± 210	1 305 ± 185	1409 ± 213

PN, parenteral nutrition.

¹P = 0.04 vs normal value.

²P = 0.04 vs normal value.

³P = 0.02 vs before PN.

Table 3 Complications observed during perioperative parenteral nutrition

Type of complications	Non-malnutrition group	Malnutrition group
Infectious
Pneumonia	2 (Pneumococcus)	1 (Pneumococcus)
Bacteremia	1 (Escherichia coli)	0
Abdominal Abscess	1 (Enterococcus)	1 (E.coli)
Noninfectious
Anastomotic leak	1	1
Wound dehiscence	1	2
Liver cholestasis	1 (Tbil = 1.6 mg/dL)	1 (Tbil = 1.4 mg/dL)
Catheter-related	0	0
Total	7	6