Cloning and characterization of a novel hepatitis B virus core binding protein C12

Table 1 Binding protein of C12 protein screened by yeast two-hybrid

Homeobox gene	Homogeneity %	Clones
Cathepsin B	99	1
Apolipoprotein M	98	1
Cytochrome C oxidase II	97–99	3
Receptor JAK (EPHB4) variation factor	99	1
KH splicing regulation protein (KSRP)	98	1
Phosphatidylinositol deacylase	97	1
poly-glucose Q transcriptional variation factor 1
Ferritin light chain	99	2
Ornithine decarboxylase 1	99	1
Metallothionein 2A	98–100	3
Blood coagulation factor IX	100	1
Acetolactate synthase	99	1
Calpain	98	1
Exo-nucleus triphosphate diplo-phosphoinostide	99	1
hydrolase 5
Plasma globulin inhibitive factor H4	99	1
Novel gene	100	2

Table 2 Differential expression genes upregulated by C12 gene

GenBank number	Homeobox gene
208	Insulin receptor (INSR),
5500	SUMO-1 activating enzyme subunit 1 (SAE1),
6292	Tumor susceptibility gene 101 (TSG101),
12248	Selenophosphate synthetase 2 (SPS2),
6217	Serine (or cysteine) proteinase inhibitor, clade I
	(neuroserpin), member 2 (SERPINI2),
16614	TRAF and TNF receptor-associated protein (TTRAP),
6437	ADP-ribosyltransferase-like 1 (ADPRTL1)
33306	Caspase 4, apoptosis-related cysteine protease
	(CASP4), transcript variant gamma,
L04731	Translocation T (4:11) of ALL-1 gene
2085	Glutathione peroxidase 4 (phospholipid
	hydroperoxidase) (GPX4),
4728	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
	21 (DDX21),
2624	Prefoldin 5 (PFDN5), transcript variant 1,
6415	Serine palmitoyl transferase, long chain base
	subunit 1 (SPTLC1),
4127	G protein pathway suppressor 1 (GPS1),
14887	Hypothetical protein from BCRA2 region
660	Transforming growth factor, beta 1 (TGF-β 1),