B7 molecule mRNA expression in colorectal carcinoma

Table 1 B7 family molecule expression in colorectal cancer cells and TIL (mean±SD)

B7 molecule	Tumor cell	TIL
B7-1:	1.29 ± 0.63	0.45 ± 0.28a
B7H1:	1.38 ± 0.71	0.65 ± 0.33a
B7H2:	0.76 ± 0.54	0.38 ± 0.19a
ICOS:	1.62 ± 0.82	0.53 ± 0.27a

^aP<0.05 vs tumor cell.

Table 2 Relationship between depth of tumor invasion and B7 family molecule expression (mean±SD)

B7 molecule	Tumor cell			TIL
	T2	T3	T4	T2	T3	T4
B7-1:	1.22 ± 0.82	1.28 ± 0.70	1.35 ± 0.42	0.36 ± 0.43	0.50 ± 0.25	0.43 ± 0.24
B7H1:	1.43 ± 0.63	1.55 ± 0.76	1.01 ± 0.63	0.66 ± 0.25	0.76 ± 0.36a	0.42 ± 0.21
B7H2:	0.62 ± 0.05	0.91 ± 0.69	0.56 ± 0.28	0.42 ± 0.21	0.39 ± 0.19	0.33 ± 0.18
ICOS:	1.59 ± 1.14	1.77 ± 0.78	1.35 ± 0.78	0.48 ± 0.35	0.53 ± 0.23	0.59 ± 0.33

^aP<0.05 vs T2, T4.

Table 3 Relation between tumor metastasis and B₇ family molecule expression (mean±SD)

B7 molecule	Tumor cell		TIL
	Metastasis	Nometastasis	Metastasis	Nometastasis
B7-1:	1.08 ± 0.59	1.31 ± 0.64	0.34 ± 0.18	0.46 ± 0.28
B7H1:	0.70 ± 0.00	1.45 ± 0.71a	0.29 ± 0.04	0.68 ± 0.35a
B7H2:	0.59 ± 0.01	0.78 ± 0.57	0.47 ± 0.33	0.37 ± 0.18
ICOS:	0.63 ± 0.04	1.72 ± 0.80a	0.24 ± 0.06	0.56 ± 0.27a

^aP<0.05 vs metastasis.