Over-expression of fibroblast growth factor receptor 3 in human hepatocellular carcinoma

Table 1 Different expressions of transcription and translation-re-lated gene in HCC

Gene name	Codingnumber
Most over-expressed genes in HCC
Translational initiation factor EIF-2, alpha subunit	1154
Homo sapiens GTP binding protein mRNA complete code	38708
Human mRNA for elongation factor-1-β	35748
Human CDC2-related protein kinase mRNA	1793
Fibroblast growth factor receptor 3	36165
Elongation factor-1-γ	1676
mRNA for erythropoietin receptor	396
Human G protein-coupled receptor	1097
Glutathione S-transferase	31919
Homo sapiens NADH-ubiquinone oxidoreductase subunit CI-SGDH	32232
Least expressed genes in HCC
Human insulin-like growth factor binding protein gene	1232
Homo sapiens mRNA for TGF-β IIR α	1815
Heterogeneous nuclear ribonucleoprotein H	41292
Polyubiquitin Ubc	32334
Nucleic acid binding protein gene	32841
MAP2K5	33071
Cyclin D1	40436

Table 2 Patients demographic features and FGFR3 expression (n = 43)

Demographic features	n = 43
Age (yr)	59.79
Gender
Male	34
Female	9
Hepatitis B
Positive	28
Negative	15
FGFR3 expression (%)
0	3 (6.98)
+	20 (46.51)
++	20 (46.51)

Table 3 Relationship between FGFR3 expression, HCC differentiation and nuclear grade (n = 43)

Differentiation				Nuclear grade
FGFR3 expression	Well	Moderate	Poor	1	2	3	4
0	3	0	0	3	0	0	0
1	1	17	2	0	16	4	0
2	0	11	9	0	9	11	0