Blood micronutrient, oxidative stress, and viral load in patients with chronic hepatitis C

Table 1 lasma concentrations of Zn, Cu, Fe, and Se in patients with chronic hepatitis C and healthy controls (mean±SE)

Groups	Plasma
	Zn (mg/L)	Cu (mg/L)	Fe (mg/L)	Se (μg/L)
Patients	0.13 ± 0.01a	1.68 ± 0.08a	0.56 ± 0.04	159.12 ± 5.30a
Healthy controls	0.55 ± 0.06	0.53 ± 0.03	0.57 ± 0.03	216.69 ± 7.44

^aP<0.05 vs healthy controls.

Table 2 rythrocyte levels of Zn, Cu, Fe, and Se in patients with chronic hepatitis C and healthy controls (mean±SE)

Groups	Erythrocytes
	Zn (mg/L)	Cu (mg/L)	Fe (mg/L)	Se (μg/L)
Patients	0.79 ± 0.05a	0.52 ± 0.05a	1369.8 ± 88.6	55.09 ± 3.79a
Healthy controls	1.40 ± 0.10	0.09 ± 0.01	1075.9 ± 96.7	139.08 ± 5.76

^aP<0.05 vs healthy controls.

Table 3 MDA levels, SOD, GR, and GPX activities in patients with chronic hepatitis C and healthy controls (mean±SE)

Group	Parameters1
	MDAPlasma (nmol/mL)	RBC (nmol/g protein)	SOD (U/g Hb)	GR (mU/g Hb)	GPX[nmol/(min·mL)]
Patients	0.41 ± 0.02a	0.33 ± 0.02a	17.95 ± 0.51a	40.10 ± 2.48a	38.95 ± 1.99a
Healthy controls	0.15 ± 0.01	0.19 ± 0.02	15.24 ± 0.45	30.15 ± 2.69	51.26 ± 2.66

^aP<0.05 vs healthy controls.

¹MDA: malondialdehyde; SOD: superoxide dismutase; GR: glutathione reductase; GPX: glutathione peroxidase.