Effects of magnolol and honokiol derived from traditional Chinese herbal remedies on gastrointestinal movement

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Jul 28, 2005 (publication date) through Nov 2, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2005; 11(28): 4414-4418
Published online Jul 28, 2005. doi: 10.3748/wjg.v11.i28.4414

Table 1 Effects of magnolol and honokiol on the two contractile components of Ach (%, mean±SD, n = 6)

^bP<0.01 vs others.

Table 2 Effects of magnolol and honokiol on gastrointestinal movement in mice (mean±SD, n = 20)

Group (mg/kg)	Rate of gastric residual nuclide (%)	Intestinal propulsive ratio (%)
Control	50.05±12.74	47.92±8.49
Cisapride	22.26±9.17^b	61.92±11.77^b
Magnolol 0.5	24.61±10.90^b	57.14±13.12^b
Magnolol 2	26.40±12.14^b	55.46±11.26^b
Magnolol 20	25.96±8.44^b	60.30±10.52^b
Honokiol 0.5	24.91±11.30^b	53.57±9.54^a
Honokiol 2	34.11±12.25^b	54.54±8.29^b
Honokiol 20	33.22±13.64^b	53.53±9.90^a

^aP<0.05,

^bP<0.01 vs control.

Citation: Zhang WW, Li Y, Wang XQ, Tian F, Cao H, Wang MW, Sun QS. Effects of magnolol and honokiol derived from traditional Chinese herbal remedies on gastrointestinal movement. World J Gastroenterol 2005; 11(28): 4414-4418
URL: https://www.wjgnet.com/1007-9327/full/v11/i28/4414.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i28.4414