Brief Reports
Copyright ©The Author(s) 2005.
World J Gastroenterol. Jul 28, 2005; 11(28): 4414-4418
Published online Jul 28, 2005. doi: 10.3748/wjg.v11.i28.4414
Table 1 Effects of magnolol and honokiol on the two contractile components of Ach (%, mean±SD, n = 6)
Group (mol/L)First phaseSecond phase
Magnolol 10389.087.32b86.898.04b
Magnolol 10483.8011.18b92.974.70b
Magnolol 10566.4812.95b75.3910.53b
Honokiol 10474.546.75b91.113.89b
Honokiol 10568.9310.90b82.115.51b
Honokiol 10645.684.92b78.955.83b
Table 2 Effects of magnolol and honokiol on gastrointestinal movement in mice (mean±SD, n = 20)
Group (mg/kg)Rate of gastric residual nuclide (%)Intestinal propulsive ratio (%)
Control50.05±12.7447.92±8.49
Cisapride22.26±9.17b61.92±11.77b
Magnolol 0.524.61±10.90b57.14±13.12b
Magnolol 226.40±12.14b55.46±11.26b
Magnolol 2025.96±8.44b60.30±10.52b
Honokiol 0.524.91±11.30b53.57±9.54a
Honokiol 234.11±12.25b54.54±8.29b
Honokiol 2033.22±13.64b53.53±9.90a