Copyright
©The Author(s) 2005.
World J Gastroenterol. Jul 14, 2005; 11(26): 4124-4126
Published online Jul 14, 2005. doi: 10.3748/wjg.v11.i26.4124
Published online Jul 14, 2005. doi: 10.3748/wjg.v11.i26.4124
Hereditary cancer | Definition | Reference | |
1 | Li-Fraumeni syndrome (LFS) | A proband with a sarcoma under 45 yr | 8 |
Plus 1st degree relative under 45 yr with any cancer | |||
Plus an additional 1st or 2nd degree relative in the same lineage with | |||
any cancer aged under 45 yr or sarcoma at any age | |||
2 | Familial gastric cancer (FGC) | At least two gastric cancer patients within 1st degree relatives | 6 |
and one patient diagnosed before the age of 50 | |||
2-(1) | Hereditary diffuse gastric cancer (HDGC) | (1) Two or more diffuse gastric cancer patients in 1st or 2nd degree relatives, | 15 |
with at least one diagnosed before the age of 50 | |||
(2) Three or more diffuse gastric cancer patients in 1st or 2nd degree relatives, | |||
indepently of age of onset | |||
2-(2) | Familail intestinal gastric cancer (FIGC) | At least three relatives should have intestinal gastric cancer and one of them | 15 |
should be a 1st degree relative of the other two | |||
Plus at least two successive generations should be affected plus in one of the relatives, gastric cancer shoul be diagnosed before the age of 50 |
- Citation: Kim IJ, Kang HC, Shin Y, Yoo BC, Yang HK, Park JG. Familial gastric cancers with Li-Fraumeni Syndrome: A case repast. World J Gastroenterol 2005; 11(26): 4124-4126
- URL: https://www.wjgnet.com/1007-9327/full/v11/i26/4124.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i26.4124