Differences in biological features of gastric dysplasia, indefinite dysplasia, reactive hyperplasia and discriminant analysis of these lesions

Table 1 Expressions of PCNA in different lesions.

PCNA expression	RH	IDys	Dys	IGC
-	0	0	0	0
+	25	9	0	0
++	17	24	9	1
+++	1	2	15	11
++++	0	0	11	24
Total	43	35	35	36

Table 2 Results of discriminant analysis and its cross-validated various lesions.

Membership	Predicted group					Total
	PATH	RH	IDys	Dys	IGC
Original Count	RH	29 (67.4)	13 (30.2)	1 (2.3)	0 (0.0)	43
	IDys	9 (25.7)	24 (68.6)	1 (5.7)	0 (0.0)	35
	Dys	0 (0.0)	3 (8.8)	24 (70.6)	7 (20.6)	34
	IGC	0 (0.0)	1 (3.0)	4 (12.1)	28 (84.8)	33
	Ungrouped cases	1 (50.0)	1 (50.0)	0 (0.0)	0 (0.0)	2
Cross-validated Count	RH	28 (69.8)	12 (32.6)	1 (2.3)	0 (0.0)	43 (100.0)
	IDys	14 (40.0)	20 (54.3)	1 (5.7)	0 (0.0)	35 (100.0)
	Dys	0 (0.0)	4 (11.8)	24 (67.6)	7 (20.6)	35 (100.0)
	IGC	0 (0.0)	3 (3.0)	19 (15.2)	47 (81.8)	69 (100.0)

The discriminant functions are as follows: Y_RH = -11.354+4.573MUC5AC+30.432Ki-67+5.027PCNA. Y_IDys = -15.404+3.895MUC5AC+39.669Ki-67+6.032 PCNA. Y_Dys = -31.031+0.823MUC5AC+60.027Ki-67+9.605 PCNA .Y_IGC = -45.525-0.322MUC5AC+74.916Ki-67+11.542PCNA.