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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Apr 28, 2005; 11(16): 2462-2466
Published online Apr 28, 2005. doi: 10.3748/wjg.v11.i16.2462
Published online Apr 28, 2005. doi: 10.3748/wjg.v11.i16.2462
Table 1 Distribution of age and course of the illness.
| Age and course | 2000s group n (%) | 1990s group n (%) | |
| Age (yr) | <30 | 21 (17.2) | 19 (17.9) |
| 30- | 31 (25.4) | 33 (31.1) | |
| 40- | 39 (32.0) | 21 (19.8) | |
| 50- | 14 (11.5) | 21 (19.8) | |
| 60- | 17 (13.9) | 12 (11.3) | |
| Total course of the illness (yr) | <1.0 | 61 (50.0)a | 33 (31.7) |
| 1.0- | 48 (39.3) | 40 (37.7) | |
| 5.0- | 6 (4.9)a | 18 (17.0) | |
| 10.0- | 7 (5.7)a | 15 (17.0) | |
| Course of present | |||
| flare-up (yr) | <0.5 | 85 (69.7) | 71 (67.0) |
| 0.5- | 20 (16.4) | 17 (16.0) | |
| 1.0- | 17 (13.9) | 18 (17.0) |
Table 2 Clinical types of the illness.
Table 3 Frequency and property of stool.
| Frequency of stool and property | 2000s group n (%) | 1990s group n (%) | |
| Frequency of stool | <21 | 53 (43.4) | 40 (37.7) |
| (times per week) | 21- | 57 (46.2) | 48 (45.5) |
| 42- | 12 (9.8) | 18 (17) | |
| Property of stool | Nonmucous and bloody stool | 36 (29.5) | 27 (25.5) |
| Slight mucous and bloody stool | 43 (35.2) | 30 (28.3) | |
| Slight mucous and bloody stool | 43 (35.2) | 49 (46.2) |
Table 4 Clinical, colonoscopic and histological classifications.
| Classifications | Clinical n (%) | Colonoscopic n (%) | Histological n (%) | |||
| 2000s group | 1990s group | 1990s group | 2000s group | 2000s group | 1990s group | |
| Grade 1 | 64 (52.5) | 41 (38.7) | 25 (20.5) | 10 (9.4) | 25 (20.5) | 14 (13.3) |
| Rade 2 | 53 (43.4) | 57 (53.8) | 46 (37.7) | 36 (34.0) | 46 (37.7) | 33 (31.1) |
| Grade 3 | 5 (4.1) | 8 (7.5) | 37 (30.3) | 11 (10.4) | 39 (32.) | 40 (37.7) |
| Grade 4 | 14 (11.5) | 49 (46.2) | 12 (9.8) | 19 (17) | ||
Table 5 Comparison of clinical, colonoscopic and histological classifications before and after treatment with SASP in 110 patients.
| Classification | Clinical n (%) | Colonoscopic n (%) | Histological n (%) | |||
| Before | After | Before | After | Before | After | |
| Grade 0 | 0 | 79 (71.8) | 0 | 24 (21.8) | 0 | 18 (16.4) |
| Grade 1 | 56 (50.9) | 27 (24.6) | 7 (6.4) | 56 (50.9) | 21 (19.1) | 67 (60.9) |
| Grade≥2 | 54 (49.1) | 4 (3.6) | 103 (93.6) | 30 (27.3) | 89 (80.9) | 25 (22.7) |
| P | <0.01 | <0.01 | <0.01 | |||
Table 6 Comparison of efficacy in the patients with different types of the illness treated with SASP.
| The overall effects | First episode n (%) | Chronic relapse n (%) | Chronic persistent n (%) |
| Complete remission | 10 (18.9) | 3 (7.5) | 1 (5.9) |
| Partial remission | 28 (52.8) | 16 (40.0) | 6 (35.3) |
| Improvement | 9 (17.0) | 15 (37.5) | 6 (35.3) |
| Inefficiency | 6 (11.3) | 6 (15.0) | 4 (23.5) |
| P <0.05 |
- Citation: Chen QK, Yuan SZ, Wen ZF, Zhong YQ, Li CJ, Wu HS, Mai CR, Xie PY, Lu YM, Yu ZL. Characteristics and therapeutic efficacy of sulfasalazine in patients with mildly and moderately active ulcerative colitis. World J Gastroenterol 2005; 11(16): 2462-2466
- URL: https://www.wjgnet.com/1007-9327/full/v11/i16/2462.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i16.2462