Copyright
©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Apr 28, 2005; 11(16): 2456-2461
Published online Apr 28, 2005. doi: 10.3748/wjg.v11.i16.2456
Published online Apr 28, 2005. doi: 10.3748/wjg.v11.i16.2456
Table 1 Diseases and surgical techniques.
| Diseases | No. of patients(n = 62) | Surgical techniques | |
| PD (n = 52) | PPPD (n = 10) | ||
| Pancreas cancer | 29 | 26 | 3 |
| Ampullary cancer | 14 | 10 | 4 |
| Bile duct cancer | 13 | 12 | 1 |
| Islet cell cancer | 2 | 1 | 1 |
| Duodenal cancer | 1 | 1 | 0 |
| Chronic pancreatitis | 1 | 1 | 0 |
| Pancreatic cystadenoma | 1 | 0 | 1 |
| Gastric cancer | 1 | 1 | 0 |
Table 2 General risk factors for pancreatic leakage [n (%)].
| Parameters | Leakage group Parameters (n = 12) | Nonleakage group(n = 45) | P |
| Age (yr) | 59.8±10.04 | 57.1±11.37 | 0.487 |
| Gender | 0.166 | ||
| Male | 4 (10.5)1 | 34 (89.5)1 | |
| Female | 6 (25)1 | 18 (75)1 | |
| History of jaundice | 0.733 | ||
| Yes | 4 (13.3)1 | 26 (86.7)1 | |
| No | 6 (18.8)1 | 26 (81.2)1 | |
| Preoperative | |||
| serum-albumin | >0.95 | ||
| Normal | 10 (16.9)1 | 49 (83.1)1 | |
| Low | 0 (0)1 | 3 (100)1 | |
| Pathology | 0.3122 | ||
| Pancreas cancer | 3 (10.3)1 | 26 (89.7)1 | |
| Ampullary cancer | 3 (21.4)1 | 11 (78.6)1 | |
| Bile duct cancer | 3 (23.1)1 | 10 (76.9)1 | |
| Islet cell tumor | 1 (50)1 | 1 (50)1 | |
| Duodenal cancer | 0 (0)1 | 1 (100)1 | |
| Chronic pancreatitis | 0 (0)1 | 1 (100)1 | |
| Pancreatic | |||
| cystadenoma | 0 (0)1 | 1 (100)1 | |
| Gastric cancer | 0 (0) | 1 (100) | |
| Octreotide | 0.493 | ||
| Used | 6 (20.7)1 | 23 (79.3)1 | |
| Non-used | 4 (12.1)1 | 29 (87.9)1 | |
| Postoperative stay (d) | 32.7±12.37 | 26.4±13.51 | 0.177 |
Table 3 Intraoperative risk factors for pancreatic leakage [n (%)].
| Parameters | Leakage group (n = 12) | Nonleakage group (n = 45) | P |
| Type of resection | 0.629 | ||
| PD | 8 (15.1)1 | 45 (84.9)1 | |
| PPPD | 2 (22.2)1 | 7 (87.8)1 | |
| Anastomotic technique | 0.43 | ||
| Duct-to-mucosa | 1 (6.25)1 | 15 (93.75)1 | |
| Invagination | 9 (19.6)1 | 37 (80.4)1 | |
| Pancreatic size (mm) | 0.002 | ||
| ≥3 | 2 (4.88)1 | 39 (95.12)1 | |
| <3 | 8 (38.1)1 | 13 (61.9)1 | |
| Pancreatic texture | 0.004 | ||
| Hard | 1 (2.94)1 | 33 (97.06)1 | |
| Soft | 9 (32.1)1 | 19 (67.9)1 | |
| Operative time (h) | 7.052.40 | 6.342.02 | 0.325 |
| Intraoperative | |||
| blood loss (mL)2 | 400 (0, 1250) | 350 (0, 1 200) | 0.352 |
Table 4 Multivariate logistic regression for pancreatic leakage.
| Parameters | P | Odds ratio | CI |
| Anastomotic | |||
| technique | |||
| Duct-to-mucosa | - | 1 | |
| Invagination | 0.128 | 9.967 | 0.514-193.15 |
| Pancreatic size (mm) | |||
| ≥3 | - | 1 | |
| <3 | 0.007 | 11.867 | 1.96-71.86 |
| Pancreatic texture | |||
| Hard | - | 1 | |
| Soft | 0.017 | 15.445 | 1.629-146.46 |
- Citation: Yang YM, Tian XD, Zhuang Y, Wang WM, Wan YL, Huang YT. Risk factors of pancreatic leakage after pancreaticoduodenectomy. World J Gastroenterol 2005; 11(16): 2456-2461
- URL: https://www.wjgnet.com/1007-9327/full/v11/i16/2456.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i16.2456