Oxidative stress and nitric oxide in rats with alcohol-induced acute pancreatitis

Table 1 Histopathologic lesions observed in pancreas and lung.

	Pancreas					Lung
	Edema	Hemorrhage	Hyperemia	Necrosis	PMNinfiltration	PMN and lymphocytic infiltration	Alveolar neutrophilic exudation	Hyperemia	Focal atelectasia
Control	+/-	-	+	-	-	-	-	+/-	-
AP	+	+	+	++	+	+	+	+	+

The semiquantitative evaluation scale was the mean of the lesions observed in each group evaluated by independent observers: -, no lesion; +/-, minimal lesion; +, mild lesion; ++, moderate lesion; +++, intense lesion. AP: acute pancreatitis.

Table 2 Correlation between studied parameters in control and experimental groups.

	Control group (n = 15)	AP group (n = 25)
GSHpanc-NOxpanc	r = 0.757d
GSHlung-NOxlung	r = 0.533a
GSHplasma-NOxplasma		r = -0.426a
GSHpanc-TBARSpanc		r = 0.462a
TBARSplasma-TBARSpanc		r = -0.402a
TBARSplasma-NOxpanc		r = -0.654b
TBARSpanc-TBARSlung		r = 0.650b

AP: acute pancreatitis, NOx: nitrite plus nitrate.

^aP<0.05,

^bP<0.01,

^dP<0.001.