Traditional Chinese medicine syndromes of chronic hepatitis B with precore mutant

Table 1 The cases, sex, and age of three groups.

	n	Ration of sex (M:F)	Age (yr)
			Mean	Range
Mutant	70	11:03	29.10±1.02	18-56
Wild-type	70	61:9	28.96±0.83	17-57.5
Healthy control	30	5:1	28.85±1.40	17-55

M: male; F: female.

Table 2 Distribution of syndrome-types based on TCM in mutant and wild-type groups.

Subtype	Pre-core Mutant
	-	+
DHSM	36	17
LSSD	7	12
YDLK	7	5
BSIC	4	7
DHBS	11	25
YDSK	5	4
Mild hepatitis	41	23
Medium hepatitis	22	39
Severe hepatitis	7	8

DHSM: damp-heat stasis in the middle-jiao LSSD: liver Qi stagnation and spleen deficiency YDLK: Yin deficiency of liver and kidney BSIC: blood stasis into collateral DHBS: damp heat complicated with blood stasis YDSK: Yang deficiency of spleen and kidney.

Table 3 Variant analysis between three groups and Dunnett-t test.

	Groups	Cases	Mean±SD
CD4+	Control group	30	38.27±4.00
	Wild-type group	70	29.9±6.14ab
	Mutant group	70	28.69±5.38b
CD8+	Control group	30	23.9±2.96
	Wild-type group	70	22.4±4.60
	Mutant group	70	23.53±4.80
CD4+/CD8+	Control group	30	1.59±0.163
	Wild-type group	70	1.36±0.31ab
	Mutant group	70	1.26±0.28b
DNA	Wild-type group	70	4.94±1.16a
	Mutant group	70	5.89±1.88

One-way ANOVA variant analysis was made between the three groups. During Dunnett-t test control group was taken as object group, other groups comparing with the object group.

^aP<0.05 Comparison between two study groups,

^bP<0.01 comparison made to control group.

Table 4 Comparison of DNA content in mutant group and wild-type group.

		Mean±SD
Mutant group	Mild	5.934±1.936
	Medium	5.558±1.687
	Severe	6.661±2.128
Wild-type group	Mild	4.664±1.1361
	Medium	4.999±1.196
	Severe	5.445±0.975