p62 expression in primary carcinomas of the digestive system

Table 1 Results of IHC for p62 in gastrointestinal and liver cancers.

Type of cancer	Number of cases	p62 positivity No. (%)
Gastrointestinal	60	60 (100)b
Esophageal	22	22 (100)
Gastric	17	17 (100)
Colorectal	21	21 (100)
Hepatocellular	40	27 (67.5)

^bP<0.01 vs HCC.

Table 2 Correlation of p62 expression with histological grade and mean Ki-67 LI in gastrointestinal and liver cancers.

Histological grade	Anti-p62 ICH				P
	-	+	++	+++
Esophageal carcinoma
High	0	1	5	4
Moderate	0	4	1	4
Poor	0	0	1	2	0.8246
Gastric and colorectal carcinoma
High + moderate	0	0	4	21
Poor + undif.	0	0	4	5
MAC	0	4	0	0	<0.0001
HCC
I	2	0	0	0
II	5	6	3	3
III	6	2	4	9	0.0322
Mean Ki-67 LI	7.53±14.84	17.89±14.42	29.29±16.55	28.30±18.73a

ICH: immunohistochemistry; undif: undifferentiated; MAC: mucinous adenocarcinoma; LI: labeling index

^aP<0.05 vs negative (–) p62 expressing tissues.