Clinical phenotype and prevalence of hereditary nonpolyposis colorectal cancer syndrome in Chinese population

Table 1 Condition of all chosen papers and their studied districts.

Number	First authors	District	Source of references
1	Zhen-Jun Wang	Beijing	Journal of Coloproctological Surgery,2001, 7(3): 3-4
2	Ding-Cun Luo	Zhejiang	China Oncology, 2000, 10(2): 145-146, 152
3	Shi-Lin Wang	Beijing	Journal of General Hospital of Air Force, 2000, 16(1):33-34,37
4	Yan-Ting Jian	Guangdong	J First Mil Med Univ, 2001, 21(1): 15-16
5	Shi-Xin Xu	Jiangsu	China Oncology, 1998, 8(1): 56-58
6	Shan-Jing Mo	Shanghai	Chin J Dig, 1996, 16(6): 326-328
7	Jian-Sheng Li	Zhejiang	Journal of Practical Oncology, 2000, 15(1): 46-47
8	Meng-Hong Sun	Shanghai	Natl Med J China, 2001, 81(20): 1268-1269
9	Zhi-Zhuang Li	Shandong	Acta Academiae Medicinae Nantong, 2001,21(4):437
10	Chen-Yi Wang	Hunan	Hunan Medical Journal, 1998, 15(1): 64
11	Gang Ye	Zhejiang	Medical Journal of Ningbo, 1997, 9(5): 226
12	Liang Xu	Sichuan	The Practical Journal of Cancer, 2002,17(4): 395-397
13	Zhen-Jun Wang	Beijing	Chin J Gastrointest Surg, 2000, 3(4): 217-219
14	Yi-Tao Jia	Hebei	Chin J Med Genet, 1999, 16(3): 200
15	Hei-Ying Jin	Shanghai	J Clin Surg, 2001, 9(6): 356-357
16	Shi-Lin Wang	Beijing	Journal of Oncology, 2002, 8(1): 24-26
17	Guo-Fu Chen	Zhejiang	China Oncology, 2003, 13(3): 240-242
18	Li-Xin Liu	Beijing	Chinese Journal of Coal Industry Medicine, 2002, 5(7):643-644
19	SC Wei	Taiwan	J Formos Med Assoc, 2002, 101(3): 206-209
20	San-Jun Cai	Shanghai	World J Gastroenterol, 2003, 9(2): 284-287
21	Gang Chen	Tianjin	Chinese Journal of Clinical Oncology, 2003, 30(4):247-249
22	Hua-Wei Jin	Guangdong	Chinese Journal of Practical Surgery, 2000, 20(4): 231-232
23	Zhi-Qiang Xue	Guangdong	Guangdong Medical Journal, 2003, 24(7): 752-753
24	Shi-Lin Wang	Beijing	Chin J Gen Surg, 2000, 15(11): 667-668

Table 2 Extracolonic tumors found in HNPCC families.

Extracolonic tumor	Number of AC (%)	Number of AC II (%)
Gastric cancer	36 (28.8)	49 (28.2)
Endometrial cancer	28 (22.4)	36 (20.7)
Ovarian cancer	6 (4.8)	9 (5.2)
Small intestinal cancer	3 (2.4)	9 (5.2)
Esophageal cancer	6 (4.8)	9 (5.2)
Pancreatic cancer	5 (4.0)	6 (3.4)
Breast cancer	5 (4.0)	7 (4.0)
Cancer of nasopharynx/larynx	2 (1.6)	3 (1.7)
Malignant lymphoma	2 (1.6)	2 (1.2)
Leukemia	1 (0.8)	1 (0.6)
Thyroid cancer	5 (4.0)	5 (2.9)
Lung cancer	4 (3.2)	8 (4.6)
Hepatocarcinoma	10 (8.0)	11 (6.3)
Bladder carcinoma	1 (0.8)	3 (1.7)
Cancer of brain	3 (2.4)	5 (2.9)
Ureter/renal pelvis cancer	0 (0.0)	1 (0.6)
Carcinoma of kidney	2 (1.6)	2 (1.2)
Skin cancer	2 (1.6)	2 (1.2)
Osteosarcoma	0 (0.0)	2 (1.2)
Carcinoma of prostate	1 (0.8)	1 (0.6)
Malignant teratoma	1 (0.8)	1 (0.6)
Cancer of parotid gland	1 (0.8)	1 (0.6)
Liposarcoma	1 (0.8)	1 (0.6)
Total	125 (100.0)	174 (100.0)