Diagnostic evaluation of acute pancreatitis in two patients with hypertriglyceridemia

Table 1 Laboratory data on admission

		Case 1	Case 2	[Normal range]
Urinalysis
pH		7.0	6.0	[4.8-7.5]
Sugar		(±)	(+)	[ - ]
Protein		(-)	(±)	[ - ]
Occult		(-)	(-)	[ - ]
Hematology
WBC	(/mm3)	10800	26000	[4000-9000]
RBC	(/mm3)	387 × 104	474 × 104	[350 × 104-550 × 104]
Hemoglobin	(g/dL)	10.1	20.8	[12-18]
Platelet	(/mm3)	18.2 × 104	32.1 × 104	[10 × 104-40 × 104]
ESR	(mm/hr)	48	31	[< 20]
Blood chemistry
GOT	(IU/L)	16	26	[8-40]
GPT	(IU/L)	15	39	[6-35]
LDH	(IU/L)	410	392	[100-450]
Al-P	(IU/L)	158	198	[100-340]
LAP	(IU/L)	33	58	[110-210]
γ GTP	(IU/L)	71	71	[< 70]
ChE	(IU/L)	272	554	[186-406]
ZTT	(U)	5	2	[4-12]
Total Bilirubin	(mg/dL)	0.8	1	[0.3-1.0]
TC	(mg/dL)	175	902	[150-220]
TG	(mg/dL)	673	10340	[50-150]
HDL-C	(mg/dL)	18	16	[35-70]
Total Protein	(g/dL)	6.1	7.6	[6.5-8.0]
Albumin	(g/dL)	3.2	3.1	[3.5-5.0]
BUN	(mg/dL)	8	13	[8-21]
Crea	(mg/dL)	0.53	0.65	[0.6-1.2]
Uric acid	(mg/dL)	3.2	4.6	[3.5-7.8]
Na+	(mEq/L)	139	125	[135-145]
K+	(mEq/L)	3.8	3.7	[3.5-5.0]
Cl-	(mEq/L)	107	88	[97-107]
Ca++	(mEq/L)	3.8	4.8	[4.3-5.8]
PO3-	(mg/dL)	2.6	2.7	[2.6-3.8]
CRP	(mg/dL)	9.9	13.9	[< 1.0]
HbA1C	(%)	4.8	9.0	[< 5.5]
Pancreatic enzymes
S-Amy	(IU/L)	81	22	[60-200]
P-Amy	(IU/L)	49	6	[30-95]
U-Amy	(IU/h)	114	168	[160-960]
Lipase	(IU/L)	29	54	[10-48]
Elastase I	(ng/dL)	180	270	[100-400]
Trypsin	(ng/dL)	210	234	[110-460]
PSTI	(ng/dL)	99	19.5	[6.1-14.7]

ESR: Erythrocyte sedimentation rate, TC: Total cholesterol, TG: Triglycerides, HDL-C: High density lipoprotein-cholesterol, CRP: C-reactive protein, HbA1c: Hemoglobin A1c, S-Amy: Salivary amylase, P-Amy: Pancreatic amylase, U-Amy: Urinary amylase, PSTI: Pancreatic secretory trypsin inhibitor.

Table 2 75 g OGTT and serum lipid profile

			Case 1	Case 2	[Normal range]
75 g OGTT
BS (mg/dL) Before			82	113	[< 110]
	30 min		148	198	[< 160]
	60 min		176	274	[< 160]
	120 min		159	262	[< 120]
Insulin (µU/mL) Before			20.3	9.3	[< 20]
	30 min		67.5	15.7
	60 min		86.9	27.5
	120 min		67.5	31.1
Cholesterol fraction
Total		(mg/dL)	161	199	[150-220]
VLDL		(mg/dL)		79.1	[< 38]
LDL		(mg/dL)		97.5	[56-160]
HDL		(mg/dL)	15	22.4	[35-70]
Triglycerides fraction
Total		(mg/dL)	571	382	[50-150]
VLDL		(mg/dL)		280.6	[6-84]
LDL		(mg/dL)		71.1	[10-35]
HDL		(mg/dL)		30.3	[11-28]
Apolipoproteins
Apolipoprotein AI		(mg/dL)	71	78.9	[119-155]
Apolipoprotein AII		(mg/dL)	20	29.8	[25.9-35.7]
Apolipoprotein B		(mg/dL)	154	136.6	[73-109]
Apolipoprotein CII		(mg/dL)	11.1	7.0	[1.8-4.6]
Apolipoprotein CIII		(mg/dL)	22.4	21.9	[5.8-10.0]
Apolipoprotein E		(mg/dL)	20.6	6.4	[2.7-4.3]
Post-heparin plasma enzyme activities
LPL activity (µmol FFA/mL/min)			0.048	0.181	[0.119-0.195]
LPL mass		(ng/dL)	< 20		[136-321]

OGTT: Oral glucose tolerance test, BS: Blood sugar, VLDL: Very low density lipoprotein, LDL: Low density lipoprotein, HDL: High density lipoprotein, LPL: Lipoprotein lipase, FFA: Free fatty acid, HTGL: Hepatic triglyceride lipase, LCAT: Leci-thin cholesterol acyl transferase.