Brief Reports
Copyright ©The Author(s) 2004.
World J Gastroenterol. Dec 1, 2004; 10(23): 3522-3527
Published online Dec 1, 2004. doi: 10.3748/wjg.v10.i23.3522
Table 1 Protein level of MDR associated genes (mean ± SD)
GroupMDR-1MRP-1LRP
transfected0.23 ± 0.040.15 ± 0.030.17 ± 0.03
control0.14 ± 0.030.08 ± 0.030.09 ± 0.02
P0.0360.0460.018
Table 2 mRNA level of MDR associated genes (mean ± SD)
GroupMDR-1MRP-1LRP
Transfected0.29 ± 0.060.62 ± 0.110.82 ± 0.15
Control0.10 ± 0.030.37 ± 0.090.42 ± 0.07
P0.0380.0120.014
Table 3 Changes of MDR related genes after treated with U0126 (mean ± SD)
GroupMDR-1MRP-1LRP
Transfected0.15 ± 0.030.62 ± 0.110.78 ± 0.13
Treated with U01260.08 ± 0.020.37 ± 0.090.44 ± 0.09
P0.0280.0400.020
Table 4 Changes of MDR related proteins after treated with U0126 (mean ± SD)
GroupMDR-1MRP-1LRP
Transfected0.22 ± 0.040.17 ± 0.020.14 ± 0.02
Treated with U01260.13 ± 0.040.12 ± 0.020.09 ± 0.02
P0.040.0380.04