Composite score of reflux symptoms in diagnosis of gastroesophageal reflux disease

Table 1 Gender and age distribution of 190 subjects in symptom severity groups

Severity of symptoms	Responders	Upper digestive endoscopy			24-h pH monitoring
		Subjects	Men/Women	Mean age (yr)	Subjects	Men/Women	Mean age (yr)
Normal	2102	40	17/23	45.5 ± 9.9	15	8/7	45.3 ± 10.4
Mild	332	40	20/20	46.1 ± 14.4	15	6/9	46.5 ± 13.3
Moderate	74	40	18/22	47.4 ± 9.6	10	5/5	47.4 ± 10.6
Severe	24	20	11/9	49.1 ± 10.2	10	4/6	49.7 ± 11.5
Total	2532	140	66/74	47.0 ± 11.0	50	23 /27	47.2 ± 11.5

Table 2 Relationship between SI and RE, PGER, GERD

Criteria of SI	Endoscopic examination		pH monitoring		Endoscopic or/and pH examination
	Subjects	RE (%)	Subjects	RE (%)	Subjects	RE (%)
Normal (SI = 0-2)	40	0 (0.0)	15	0 (0.0)	55	0 (0.0)
Mild (SI = 3-7)	40	3 (7.5)	15	2 (13.3)	52	4 (7.69)
Moderate (SI = 8-12)	40	11 (27.5)b	10	4 (40.0)a	45	12 (26.7)b
Severe (SI ≥ 13)	20	13 (66.5)b	10	6 (60.0)b	24	13 (54.2)b

^aP < 0.05 and

^bP < 0.01 vs normal group.

Table 3 Relationship between severity of symptoms and grade of RE

Severity of RE	Patients	SI (mean ± SD)
Grade I	19	10.63 ± 4.74
Grade II	13	11.32 ± 5.26
Grade III	7	11.85 ± 5.11
Grade IV	4	12.00 ± 4.12