Pathogenicty and immune prophylaxis of cag pathogenicity island gene knockout homogenic mutants

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Nov 15, 2004 (publication date) through Dec 11, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

H Pylori

World J Gastroenterol. Nov 15, 2004; 10(22): 3289-3291
Published online Nov 15, 2004. doi: 10.3748/wjg.v10.i22.3289

Table 1 cagA positive wildtype bacteria and their cagA knockout homogenic mutants

H pylori	cagPAI
LC11	+ wildtype
AH244	knockou cagPAI knockout of LC11
84183	+ wildtype
2-1	knockou cagPAI knockout of 84183
26695	+ wildtype
8-1	knockou cagPAI knockout of 26695

Table 2 Ultrasonic smashed substance’s protection against mice H pylori (result of urease test)

Immune project	Urease test (+)/number of animals (piece)	Protecting ratio (%)
PBS	5/5	0
CT	5/5	0
26695 SON + CT	3/5	40^a
8-1 SON + CT	2/5	60

^aP < 0.05, vs control groups.

Citation: Lin HJ, Xue J, Bai Y, Wang JD, Zhang YL, Zhou DY. Pathogenicty and immune prophylaxis of cag pathogenicity island gene knockout homogenic mutants. World J Gastroenterol 2004; 10(22): 3289-3291
URL: https://www.wjgnet.com/1007-9327/full/v10/i22/3289.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i22.3289