Prognostic and clinicopathological features of E-cadherin, α-catenin, β-catenin, γ-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma

Table 1 Background data of patients

Term	No. of cases (%)
Total	62
Age (yr)
< 50	22 (35.5)
≥ 50	40 (64.5)
Sex
Male	49 (79.1)
Female	13 (20.9)
Location
Upper thoracic	3 (4.8)
Middle thoracic	36 (56.5)
Lower thoracic	23 (37.1)
Histological grade
I	16 (25.8)
II	35 (56.5)
III	11 (17.7)
Depth of invasion
T1	2 (3.2)
T2	10 (16.1)
T3	32 (51.6)
T4	18 (29)
Lymph node metastasis
Positive	35 (56.5)
Negative	27 (43.5)

Table 2 The relationship between clinicopathology and the expression of cyclin D₁ E-cad and catenins

Type	Cases	CyclinD1		P	E-cad		P	α-cat		P	β-cat		P	γ-cat		P
		Positive	Negative		Preserved	Reduced		Preserved	Reduced		Preserved	Reduced		Preserved	Reduced
Histologicalgrade
I	16	6	10		5	11		7	9		10	6		8	8
II	35	15	20	> 0.05	5	30	< 0.05	11	24	> 0.05	24	11	> 0.05	19	16	< 0.05
III	11	6	5		0	11		1	10		6	5		3	8
Depth of invasion
T3	12	6	6	> 0.05	4	8	> 0.05	4	8	> 0.05	6	6	> 0.05	5	7	> 0.05
T4	50	31	19		6	44		15	35		34	16		25	25
Lymph node metastases
Positive	35	14	21	> 0.05	6	29	> 0.05	9	26	> 0.05	23	12	> 0.05	12	23	< 0.05
Negative	27	13	14		4	23		10	17		17	10		18	9