Brief Reports
Copyright ©The Author(s) 2004.
World J Gastroenterol. Nov 1, 2004; 10(21): 3197-3200
Published online Nov 1, 2004. doi: 10.3748/wjg.v10.i21.3197
Table 1 Spots of IFN-γ-producing splenic cells and level of anti-AFP antibody in mice (mean ± SD)
GrouphAFP/HSP70hAFPHSP70EmptyPBS
Spots ( 106 cells)95.50 ± 10.90bd23.60 ± 11.80f9.25 ± 5.447.17 ± 4.245.54 ± 2.16
Anti-AFP (µg/mL)126.50 ± 8.22bd51.72 ± 3.40f6.26 ± 4.275.83 ± 3.793.42 ± 2.35
Table 2 Comparison of tumor growth in mice injected with hAFP-transduced SP2/0 tumor cells (mean ± SD)
GroupNo. of tumor-bearing/10 d after tumor challenge/20 d after tumor challenge/
No. of mice challengeSize of tumor (mm3)Size of tumor (mm3)
hAFP/HSP702/824.43 ± 6.10bd37.41 ± 7.34bd
hAFP5/873.64 ± 8.53f381.13 ± 15.48f
HSP708/8118.24 ± 14.65785.83 ± 13.87
Empty8/8132.26 ± 17.27817.51 ± 16.25
PBS8/8149.73 ± 16.54860.53 ± 14.72