Can HB vaccine yield a booster effect on individuals with positive serum anti-HBs and anti-HBc markers ?

Table 1 Comparison of booster effect on anti-HBs levels be-tween two groups

	Anti-HBs (anti-HBc pos.)			Anti-HBs (anti-HBc neg.)
No.	Before	After 2nd	After 3rd	No.	After 2nd	After 3rd
		dose	dose		dose	dose
23338	161	578	362	22404	48	471
23306	266	293	163	13236	25	268
23310	406	295	293	13240	45	598
23304	168	417	337	24332	48	324
23116	44	86	76	24327	63	144
23140	30	37	43	24311	186	314
23139	372	456	344	24105	344	656
23129	309	459	225	17239	135	83
23105	145	451	461	17238	58	253
23119	162	269	252	17226	83	598
27138	592	387	533	17214	53	384
27128	406	494	449	23240	63	268
27130	341	272	199	23201	40	370
27103	182	148	145	23141	201	340
27137	53	328	211	23108	26	512
27001	326	424	269	17129	22	970
27109	99	122	116	17125	178	318
27133	573	373	316	17122	45	22
27120	151	420	207	17118	78	466
22222	115	438	588	17108	236	414
22225	442	417	338	17106	88	350
22214	283	293	466	17102	197	264
22206	176	282	208	13139	186	291
22205	547	275	377	13129	17	158
22201	183	193	158	13126	73	264
24120	128	558	393	13125	93	191
24107	239	356	257	13118	17	176
24140	35	426	409	13114	53	263
24141	212	275	231	13108	216	280
22138	392	534	659	13107	35	338
22130	660	643	504	13102	130	252
13214	247	331	244	13101	113	216
13223	491	315	176	14130	320	520
23235	106	232	199	14131	65	407
24137	108	472	280	14129	320	365
22202	61	205	253	18302	30	63
18238	244	302	303	18310	73	336
23322	422	463	503	16119	53	395
18223	333	314	389	16112	30	370
25122	355	315	286	16122	200	375
25139	206	361	337	16104	45	420
25129	116	391	303	16108	30	365
25121	38	119	204	16107	441	476
18220	65	507	506	16110	107	499
Total GMT	198	320	275	GMT	78	302

Table 2 Effect of a boost on antibody titers of HBsAb and measles Ab

Boost	A-HBsAb		B-HBsAb		C-HBsAb		MealsesAb
	No.	GMT	No.	GMT	No.	GMT	No.	GMT
Before	44	198	44	198	44	78	35	322
After	44	320	44	275	44	302	35	1 207

Comparison of anti-HBs induced by HB vaccination before and after a boost in HBV negative group, P < 0.05.