Gastrointestinal autonomic nerve tumors: A surgical point of view

Table 1 Clinical symptoms of 78 reported GAN tumors

Clinical symptoms	No. of patients	Percent of patients
Abdominal pain	32	41
Meaena	19	24
Abdominal mass	10	13
Weight loss	10	13
Vomiting	9	12
Fatigue	7	9
Fever	5	6
Anemia	4	5
Obstructive jaundice	2	2
No clinical symptoms	5	6

Table 2 Anatomic sites of the primary tumors (n = 120)

Location	No. of patients	Percent of patients
Stomach	45	37.5
Jejunum	26	22.0
Ileum	21	17.5
Duodenum	12	10.0
Retroperitoneum	4	3.3
Mesentery	3	2.5
Esophagus	2	1.6
Peritoneum	2	1.6
Rectum	2	1.6
Colon	1	0.8
Bladder	1	0.8
Omentum	1	0.8

Table 3 Summary of immunohistochemical findings of 120 cases

Antigens	No. of cases studied	No. Positive cases	Percent of positivity
Vimentin	103	95	92
Neuron-specific	117	105	90
Enolase
Chromogranin A	92	10	11
Synaptophysin	105	33	31
S-100 protein	117	44	38
Neurofilaments	87	14	16
Vasoactive intestinal peptide	25	5	20

Table 4 Metastases of reported GANT cases (n = 67)

Metastases at clincal presentation			Metastases in clinical follow up
	No. of patients	%		No. of patients	%
Location	8	12	Location	18	27
Liver	7	10	Liver	6	9
			Retroperitoneal 4	6
Lymph node	2	3	Local recurrence	5	7
			Omentum	3	4
Omentum	2	3	Mesentery	2	3
			Peritoneum	2	3