Relationship between microvessel density and telomerase activity in hepatocellular carcinoma

Table 1 Relationship between MVD and metastasis, capsular integrity, or size of tumor

Classification		Cases (n)	MVD (mean ± SD)
Metastasis	+	36	39.3 ± 9.6a
	-	22	32.2 ± 5.6
Capsular	-	38	38.8 ± 9.3a
	+	20	31.2 ± 5.8
Integrity	> 5 cm	42	37.3 ± 8.8
Size	≤ 5 cm	16	36.9 ± 8.7

^aP < 0.05, vs corresponding group.

Table 2 MVD in HCC and adjacent normal liver tissues

Group	Cases (n)	MVD (mean ± SD)
Adjacent normal tissue	58	13.2 ± 2.7
HCC grade I	11	19.6 ± 3.7
HCC grade II	22	29.7 ± 6.1a
HCC grade III	16	48.4 ± 10.7a
HCC grade IV	9	59.3 ± 10.5a

^aP < 0.05 vs adjacent normal tissue.

Table 3 Relationship between telomerase activity in HCC or adjacent normal liver tissues and some clinical factors

Group		HCC				Adjacent normal tissues
		Cases	Positive number	Positive rate (%)	P	Positive number	Positive rate (%)	P
Differentiation	High	11	6	54.4		0	0
	Middle	38	37	97.4		5	13.2
	Low	9	9	100	< 0.05	7	77.8	< 0.05
Size	≤ 5 cm	16	14	87.5		3	18.8
	> 5 cm	42	38	90.9	> 0.05	9	21.4	> 0.05
Capsule	-	20	16	80.0		1	5.0
Integrity	+	38	36	94.7	> 0.05	11	29.8	< 0.05
Hepatitis virus	+	48	44	91.6		1	22.9
Infection	-	10	8	80.0	> 0.05	1	10.0	< 0.05
Nod number	Mono-nod	15	12	80.0		1	6.7
	Multi-nod	43	40	93.0	> 0.05			< 0.05
Metastasis	+	36	34	94.4		10	27.8
	-	22	18	81.8	> 0.05	2	9.1	< 0.05

Table 4 Relationship between telomerase activity and MVD in HCC or adjacent normal liver tissues

Group	HCC	Adjacent normal tissue
Group with positive telomerase activity	49.3 ± 7.8a	16.2 ± 2.7a
Group with negative telomerase activity	31.2 ± 5.8	11.9 ± 1.4

^aP < 0.05 vs group with negative telomerase activity.