Brief Reports
Copyright ©The Author(s) 2004.
World J Gastroenterol. Jul 1, 2004; 10(13): 1992-1994
Published online Jul 1, 2004. doi: 10.3748/wjg.v10.i13.1992
Table 1 General data of two groups
Placebo groupGlutamine group
Age (yr)48.3 ± 12.248.3 ± 10.8
Male/Female7/36/4
Weight (kg)54.2 ± 11.156.7 ± 12.1
Table 2 Detailed clinical data of patients in two groups
GroupCase (n)SexAge (yr)DiagnosisOperation type
Gln group1Male55Cardiac orifice cancerTotal gastrectomy
2Male30Acute suppurative cholangitisCholecystectomy choledochostomy
3Female40Rectal cancerAnterior resection of rectum
4Male47Sigmoid cancerSigmoidectomy
5Male62Cardiac orifice cancerProximal subtotal gastrectomy
6Female28Rectal cancerAnterior resection of rectum
7Female52CholecystolithiasisCholecystectomy
8Male49Gastric cancerSubtotal gastrectomy
9Male60Gastric cancerSubtotal gastrectomy
10Male60Cardiac orifice cancerProximal subtotal gastrectomy
Placebo group1Male50Pancreas pseudocystCyst-jejunal Roux-en-y anastomosis
2Female56Ascending colon cancerRight semi-colectomy
3Female60Rectal cancerAnterior resection of rectum
4Female54Sigmoid cancerSigmoidectomy
5Male48Cardiac orifice cancerProximal subtotal gastrectomy
6Male43Ascending colon cancerRight semi-colectomy
7Male64Gastric cancerProximal subtotal gastrectomy
8Female29Gastric cancerProximal subtotal gastrectomy
9Male43Sigmoid cancerSigmoidectomy
10Male36Acute biliary pancreatitisSelective cholecystectomy
Table 3 Serum levels of Gln in two groups (μmol/L)
GroupBefore drug administration7 d after drug administration
Placebo group432.17 ± 142.68250.78 ± 77.10b
Gln group361.17 ± 161.25583.22 ± 171.52ad
Table 4 Serum DAO levels in two groups (U/mL)
GroupBefore drug7 d after drug
administrationadministration
Placebo group2.06 ± 0.483.18 ± 1.13
Gln group2.26 ± 0.631.25 ± 0.65bd
Table 5 Serum MDA levels in two groups (nmol/mL)
GroupsBefore drug7 d after drug
administrationadministration
Placebo group3.94 ± 0.564.85 ± 0.63b
Gln group4.46 ± 0.673.53 ± 0.59bd
Table 6 Levels of serum endotoxin in two groups (EU/mL)
GroupBefore drug7 d after drug
administrationadministration
Placebo group0.21 ± 0.070.25 ± 0.08
Gln group0.23 ± 0.050.18 ± 0.06ab
Table 7 Changes of urine L/M ratio in two groups
GroupBefore drug7 d after drug
administrationadministration
Placebo group134.00 ± 18.48194.83 ± 45.31b
Gln group146.10 ± 20.21117.47 ± 25.68ad