Copyright
©The Author(s) 2004.
World J Gastroenterol. Jul 1, 2004; 10(13): 1979-1983
Published online Jul 1, 2004. doi: 10.3748/wjg.v10.i13.1979
Published online Jul 1, 2004. doi: 10.3748/wjg.v10.i13.1979
Cell lines | IC50 (µg/mL) | Resistant time | Reverse time |
LoVo cells | 0.82 | ||
LoVo/5-FU cells | 7.37 | 8.988 | |
LoVo/5-FU cells + wild-type p53 | 1.48b | 1.804 | 4.982 |
Lane 1 | Lane 2 | Lane 3 | Lane 4 | |
MDR1/β-actin | 1.26 | 1.19 | 0.42 | 0.33 |
Time/d | 2 | 3 | 4 | 5 | 6 |
MDR1/β-actin | 1.22 | 1.24 | 1.06 | 0.86 | 0.42 |
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Citation: Yu ZW, Zhao P, Liu M, Dong XS, Tao J, Yao XQ, Yin XH, Li Y, Fu SB. Reversal of 5-flouroucial resistance by adenovirus-mediated transfer of wild-type
p53 gene in multidrug-resiatant human colon carcinoma LoVo/5-FU cells. World J Gastroenterol 2004; 10(13): 1979-1983 - URL: https://www.wjgnet.com/1007-9327/full/v10/i13/1979.htm
- DOI: https://dx.doi.org/10.3748/wjg.v10.i13.1979