Brief Reports
Copyright ©The Author(s) 2004.
World J Gastroenterol. Jul 1, 2004; 10(13): 1979-1983
Published online Jul 1, 2004. doi: 10.3748/wjg.v10.i13.1979
Table 1 Effect of wild-type p53 on LoVo/5-FU sensitivity to 5-flurouracil
Cell linesIC50 (µg/mL)Resistant timeReverse time
LoVo cells0.82
LoVo/5-FU cells7.378.988
LoVo/5-FU cells + wild-type p531.48b1.8044.982
Table 2 MDR1 expression in different cell lines
Lane 1Lane 2Lane 3Lane 4
MDR1/β-actin1.261.190.420.33
Table 3 MDR1 expression of LoVo/5-FU cells on different day after dealing with Ad-p53
Time/d23456
MDR1/β-actin1.221.241.060.860.42