Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.158
Revised: March 21, 1996
Accepted: June 15, 1996
Published online: September 15, 1996
AIM: To investigate the effect of ranitidine and cisapride in gastroesophageal reflux disease (GERD) therapy.
METHODS: 42 patients, who having reflux symptom, 24-h esophagitis confirmed by endoscopy were randomized to two groups. One group was treated by ranitidine (300 mg, bid) plus cisapride (5 mg, tid) (R + C group, n = 25), another by ranitidine (300 mg, bid) (R group, n = 24) for 4 wk.
RESULTS: (1) The symptom relief rate was 88.00% in R + C group, 58.33% in R group (P < 0.05); (2) The effective rate of esophageal pH monitoring was 84.62%, 50.00% (P > 0.05).
CONCLUSION: The results indicate ranitidine plus cisapride is more effective than ranitidine for the treatment of GERD.
- Citation: Yang L, Li CY, Wu JC, Wang YP, Wang W. Effect of ranitidine plus cisapride and ranitidine with gastroesophageal reflux disease. World J Gastroenterol 1996; 2(Suppl1): 158-158
- URL: https://www.wjgnet.com/1007-9327/full/v2/iSuppl1/158.htm
- DOI: https://dx.doi.org/10.3748/wjg.v2.iSuppl1.158
Original title:
E- Editor: Liu WX