Direct effect of croton oil on intestinal epithelial cells and colonic smooth muscle cells

Figure 1 A: Rich microvilli, enlarged nuclei and increased nucleoli in HIEC treated with CO (left); B: Abnormal nuclei with pathologic mitosis in HIEC treated with CO (right).

Figure 2 Expression of COX-2mRNA in HIEC. 1:HIEC treated with CO for 6week; 2:Control HIEC

Figure 3 Differential display of mRNA in HIEC treated with COM: 100bp ladder; C: HIEC treated by CO; N: Normal HIEC

Figure 4 A: Relaxed colonic smooth muscle cell; B: Contracted colonic smooth muscle cell

Figure 5 Direct contractile effect of CO on the colonic smooth muscle cells