Diagnostic performance of fine-needle aspiration vs fine-needle biopsy in solid pancreatic lesions based on pathologist expertise: A prospective multicenter trial

doi:10.3748/wjg.118873

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Sep 14, 2026; 32(34): 118873
Published online Sep 14, 2026. doi: 10.3748/wjg.118873

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Figure 1 Methodological flow. FNA: Fine-needle aspiration; FNB: Fine-needle biopsy.

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Figure 2 Process of participant randomization and systematization of punctures and slides. FNA: Fine-needle aspiration; FNB: Fine-needle biopsy.

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Figure 3 Patient outcomes 6 months after punctures.

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Figure 4 Comparison of sensitivity. A: Between the different pathologists; B: Between the participating centers and the different pathologists; C: Between the different needle types and pathologists; D: Between the different needle types, participating centers, and pathologists. P value based on proportion test with binomial distribution. CI: Confidence interval; HC-FMUSP: Hospital das Clínicas of the Medical School of the University of São Paulo; HC-FMRP: Hospital das Clínicas of the Medical School of Ribeirão Preto; HGF: Hospital Geral de Fortaleza; FNA: Fine-needle aspiration; FNB: Fine-needle biopsy.

Citation: Miranda Neto AA, Brunaldi VO, da Ponte Neto AM, Kemp R, dos Santos JS, Pádua JDB, Brunaldi MO, Oliveira FAA, Herculano Júnior JRL, Chacon DA, de Oliveira GHP, Ribeiro IB, Matuguma SE, de Moura EGH. Diagnostic performance of fine-needle aspiration vs fine-needle biopsy in solid pancreatic lesions based on pathologist expertise: A prospective multicenter trial. World J Gastroenterol 2026; 32(34): 118873
URL: https://www.wjgnet.com/1007-9327/full/v32/i34/118873.htm
DOI: https://dx.doi.org/10.3748/wjg.118873

Miranda Neto AA, Brunaldi VO, da Ponte Neto AM, Kemp R, dos Santos JS, Pádua JDB, Brunaldi MO, Oliveira FAA, Herculano Júnior JRL, Chacon DA, de Oliveira GHP, Ribeiro IB, Matuguma SE, de Moura EGH. Diagnostic performance of fine-needle aspiration vs fine-needle biopsy in solid pancreatic lesions based on pathologist expertise: A prospective multicenter trial. World J Gastroenterol 2026; 32(34): 118873 [DOI: 10.3748/wjg.118873]

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