Sex-specific differences in the efficacy and prognosis of 5-aminosalicylic acid therapy for ulcerative colitis: A 20-year retrospective cohort study

doi:10.3748/wjg.v32.i22.118036

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jun 14, 2026; 32(22): 118036
Published online Jun 14, 2026. doi: 10.3748/wjg.v32.i22.118036

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Figure 1 Flowchart of cohort screening and enrollment. 5-ASA: 5-aminosalicylic acid; UC: Ulcerative colitis.

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Figure 2 Kaplan-Meier curves. A: Kaplan-Meier cumulative survival curves for endoscopic mucosal healing: Comparison between the female and male cohorts after 1:1 propensity score matching; B: Kaplan-Meier colectomy-free survival curves: Comparison between the female and male cohorts after 1:1 propensity score matching. aHR: Adjusted hazard ratio; EMH: Endoscopic mucosal healing; CI: Confidence interval.

Citation: Liu ZS, Tang H, Zhang HM, Bai XY, Yang H, Li XF, Qian JM. Sex-specific differences in the efficacy and prognosis of 5-aminosalicylic acid therapy for ulcerative colitis: A 20-year retrospective cohort study. World J Gastroenterol 2026; 32(22): 118036
URL: https://www.wjgnet.com/1007-9327/full/v32/i22/118036.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i22.118036

Liu ZS, Tang H, Zhang HM, Bai XY, Yang H, Li XF, Qian JM. Sex-specific differences in the efficacy and prognosis of 5-aminosalicylic acid therapy for ulcerative colitis: A 20-year retrospective cohort study. World J Gastroenterol 2026; 32(22): 118036 [DOI: 10.3748/wjg.v32.i22.118036]

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