Correlation between radiomic features of Crohn's disease and secondary loss of response to infliximab

Figure 1 Flowchart of this study. CD: Crohn's disease; CT: Computed tomography; ROI: Region of interest.

Figure 2 Least absolute shrinkage and selection operator regression feature selection. A: Least absolute shrinkage and selection operator path; B: 10-fold cross-validation curve.

Figure 3 Model performance. A: Receiver operating characteristic of the three predictive models in the validation cohort; B: Decision curve analysis of the three predictive models in the validation cohort; C: Calibration curve of the combined model in the training cohort; D: Calibration curve of the combined model in the validation cohort.

Figure 4 Clinical-Radiomics nomogram. HBI: Harvey-Bradshaw Index; WBC: White blood cell.

Figure 5 Kaplan-Meier progression-free remission curves of patients at different risks stratified by the predictive probability of the combined nomogram. A: Training cohort; B: Validation cohort.