Relation of COVID-19 with liver diseases and their impact on healthcare systems: The Portuguese case

Figure 1 Flowchart of the studies selection process.

Figure 2 Mechanisms that may lead to liver injury in individuals with coronavirus disease 2019. An infection by severe acute respiratory syndrome coronavirus 2 may result in liver injury due to viral entry through angiotensin-converting enzyme 2 receptors on hepatocytes and cholangiocytes, pharmacological treatment, or an exaggerated immune response. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; ACE2: Angiotensin-converting enzyme 2; IL: Interleukin; TNF-α: Tumor necrosis factor-α.

Figure 3 Alterations in people's quality of life and healthcare systems due to coronavirus disease 2019.