Gallbladder Burkitt’s lymphoma mimicking gallbladder cancer: A case report

Figure 1 A contrast-enhanced abdominal computed tomography scan shows two irregular and highly contrast-enhanced masses (arrowheads and arrow) at the neck and body of the gallbladder as well as periportal lymph node enlargement, which is consistent with gallbladder cancer lymph node metastasis. A: Axial section image in the early phase showing neck of the gallbladder; B: Axial section image in the delayed phase showing neck of the gallbladder in the delayed phase; C: Coronal sectional image showing body of the gallbladder.

Figure 2 Magnetic resonance imaging reveals a hypointense tumor signal. A: T1-weighted imaging (arrowheads); B: A hyperintense signal on T2-weighted imaging (arrowheads); C: Diffusion-weighted imaging (arrowheads).

Figure 3 Endoscopic ultrasonography shows a heterogeneous echoic mass (arrows) with internal partially low echo (arrowheads). The mass extends into the lumen but does not infiltrate the serosa.

Figure 4 Histologic examination. A: Periportal lymphadenopathy and two tumors at the neck and body of the gallbladder, measuring 27 mm × 20 mm and 20 mm × 18 mm in diameter, respectively; B: Histological findings reveal monotonous lymphoid cells with hemophagocytosis by macrophages; C-E: Immunohistochemical staining for markers shows the presence of CD10 (C), BCL6 (D), and c-Myc (E) and the absence of BCL2; F: The Ki-67 index is > 80%. The white scale bars represent 1 mm.

Figure 5 Positron emission tomography reveals increased ¹⁸F-fluorodeoxyglucose uptake at the superior pancreaticoduodenal lymph nodes and hepatic radical margin. A: Superior pancreaticoduodenal lymph nodes; B: Hepatic radical margin.