Family-based Helicobacter pylori infection status and transmission pattern in central China, and its clinical implications for related disease prevention

Figure 1 Helicobacter pylori infection status of the 282 enrolled families. Values above each column are the case number and percentages of each group. A: Genotype pattern of the 419 infected subjects in the enrolled families; B: Distribution pattern of the 282 enrolled families ranged from 2-6 people; C: General Helicobacter pylori (H. pylori) infection status of 282 families; D: Genotype pattern of the 67 all member-infected families from the enrolled 282 families; E: Distribution pattern of the H. pylori infection status of the 282 enrolled families; F: Genotype pattern of the 132 H. pylori-infected families with ≥ 2 persons infected from the 282 enrolled families. Infected family: At least 1 person in a family was infected; Non-infected family: All members in a family were not infected; Type I H. pylori: H. pylori infection with type I strains; Type II H. pylori: H. pylori infection with type II strains; Mixed infection: H. pylori infection with type I and type II strains.

Figure 2 Helicobacter pylori infection status of 772 subjects in different age groups. Values above each column are the case number and its percentages in each specific age group. ^aP < 0.05 when Helicobacter pylori (H. pylori) infection rate in the age group of ≤ 18 yr was compared with other age groups. Type I H. pylori: H. pylori infection with type I strains; Type II H. pylori: H. pylori infection with type II strains.

Figure 3 Helicobacter pylori infection status between 244 couples. Values above each column are the case number and percentages of each group. A: Helicobacter pylori (H. pylori) infection status of 244 couples; B: Type I and II H. pylori genotype status of the 117 couples with 1 spouse infected; C: H. pylori genotype and sex of 117 couples with 1 spouse infected; D: H. pylori genotype status in 85 couples with both spouses infected; E: Relationship between infection and marriage duration in 244 couples. The dashed line across the figure is the trendline of both spouses infected, r = 0.98. Non-infected: All members in a couple were not infected; one spouse infected: Only 1 in a couple was infected; Type I H. pylori: H. pylori infection with type I strains; Type II H. pylori: H. pylori infection with type II strains; Mixed infection: H. pylori infection with type I and type II strains.