Quantitative multiparametric magnetic resonance imaging can aid non-alcoholic steatohepatitis diagnosis in a Japanese cohort

Figure 1 CONSORT diagram of patient pathway and inclusion into the study. mpMRI: Quantitative multiparametric magnetic resonance imaging; CAP: Controlled-attenuation parameter; MRE: Magnetic resonance elastography; NASH: Non-alcoholic steatohepatitis; NAFLD: Non-alcoholic fatty liver disease; VCTE: Vibration-controlled transient elastography.

Figure 2 Example images from each technology. A: Corrected T1 map; B: Magnetic resonance liver fat map; C: Fibroscan controlled-attenuation parameter; D: Fibroscan Liver Stiffness; E: magnetic resonance elastography liver stiffness map; and F: 2D Shear-wave elastography.

Figure 3 Receiver operator characteristic curves for discriminating those with non-alcoholic steatohepatitis (NAS ≥ 4 and ballooning > 1 or inflammation > 1) from those without. Area under the curve and confidence intervals displayed in the legend for each non-invasive measure. MRE: Magnetic resonance elastography; CAP: Controlled-attenuation parameter; cT1: Corrected T1; LSM: Liver stiffness measure; PDFF: Proton density fat fraction.

Figure 4 Receiver operator characteristic curves for discriminating those with non-alcoholic steatohepatitis (left) and those with non-alcoholic steatohepatitis with fibrosis (right). Area under the curve and confidence intervals displayed in the legend for each non-invasive measure. CAP: Controlled-attenuation parameter; VCTE: Vibration-controlled transient elastography; cT1: Corrected T1; NASH: Non-alcoholic steatohepatitis.