Poor performance of anti-mitochondrial antibodies for the diagnosis of primary biliary cholangitis in female Colombian patients: A single-center study

Figure 1 Prevalence of positivity for other antibodies, among participants with negative (left) or positive (right) anti-mitochondrial antibodies. Case/control status was defined by liver biopsy. AMAs: Anti-mitochondrial antibodies; ANAs: Anti-nuclear antibodies; ASMAs: Anti-smooth muscle antibodies; IgG: Positive immunoglobulin G, defined as a plasma concentration greater than the upper limit of the reference value; IgM: Positive immunoglobulin M, defined as a plasma concentration greater than the upper limit of the reference value.

Figure 2 Distribution of the degree of fibrosis according to positivity for anti-mitochondrial antibodies (left) or immunoglobulin M (right). Odds ratio for the association between positive anti-mitochondrial antibodies and any fibrosis: 1.63 (95% confidence interval: 0.67-4.09), odds ratio for the association between positive immunoglobulin M and any fibrosis: 11.0 (95% confidence interval: 1.73-69.9). AMAs: Anti-mitochondrial antibodies; IgM: Immunoglobulin M.