Major gastrointestinal bleeding and antithrombotics: Characteristics and management

Figure 1 Antithrombotic classes according to gastro-intestinal bleeding lesion location. Overall chi-square test P value = 0.03. All pair-wise comparisons with Bonferroni correction > 0.10 except for direct oral anticoagulant compared to AP (P value = 0.02). AP: Antiplatelet agent; DOAC: Direct oral anticoagulant; GI: Gastrointestinal; VKA: Vitamin K antagonist.

Figure 2 Antithrombotic classes according to gastro-duodenal ulcer and proton pump inhibitor use. General association statistic P value = 0.05. AP: Antiplatelet agent; DOAC: Direct oral anticoagulant; VKA: Vitamin K antagonist.

Figure 3 Antithrombotic classes according to gastro-intestinal bleeding type and in-hospital mortality. General association statistic P value = 0.09. AP: Antiplatelet agent; DOAC: Direct oral anticoagulant; VKA: Vitamin K antagonist.