Determining the role for uric acid in non-alcoholic steatohepatitis development and the utility of urate metabolites in diagnosis: An opinion review

doi:10.3748/wjg.v26.i15.1683

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Opinion Review

World J Gastroenterol. Apr 21, 2020; 26(15): 1683-1690
Published online Apr 21, 2020. doi: 10.3748/wjg.v26.i15.1683

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Figure 1 Potential pathogenic mechanisms of uric acid associated non-alcoholic fatty liver disease. NLRP3: NOD-like receptor family pyrin domain containing 3; ER: Endoplasmic reticulum; SREBP-1: Sterol regulatory element-binding protein 1; NOX4: NADPH oxidase subunit-4; ROS: Reactive oxygen species.

Citation: Brennan P, Clare K, George J, Dillon JF. Determining the role for uric acid in non-alcoholic steatohepatitis development and the utility of urate metabolites in diagnosis: An opinion review. World J Gastroenterol 2020; 26(15): 1683-1690
URL: https://www.wjgnet.com/1007-9327/full/v26/i15/1683.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i15.1683