Predicting systemic spread in early colorectal cancer: Can we do better?

Figure 1 An example showing measurement of the area of submucosal invasion on a digital slide of a pT1 colorectal cancer (green area). The position of the destroyed muscularis mucosae has been estimated. The scale bar signifies 2 mm.

Figure 2 An example of tumour budding (blue arrows) and poorly differentiated clusters (yellow arrows) at the invasive edge of a pT1 colorectal cancer. The scale bar signifies 100 µm.