Upper gastrointestinal tract involvement of pediatric inflammatory bowel disease: A pathological review

Figure 1 Hematoxylin and eosin staining. A and B: Lymphocytic esophagitis is characterized by increased intraepithelial lymphocytes, predominantly peripapillary, with absence of intraepithelial eosinophils and neutrophils [hematoxylin and eosin (H and E), 10 × and 20 ×]. C: Low power view of focally enhanced gastritis demonstrates focal dense infiltrate surrounding a gland (black arrow) with a minimal increase of lymphoplasmacytic infiltrate in the lamina propria (H and E, 4 ×); D: Focally enhanced gastritis is characterized by lymphohistiocytic infiltrate with scattered neutrophils and associated glandular damage seen on medium power view (H and E, 10 ×).

Figure 2 Duodenal manifestations of inflammatory bowel disease. Duodenal manifestations of inflammatory bowel disease include (A) focal cryptitis (black arrow) [hematoxylin and eosin (H and E), 10 ×], (B) increased intraepithelial lymphocytes (H and E, 10 ×), and (C and D) Brunner gland inflammation (black arrow) (H and E, 4 × and 10 ×).