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©The Author(s) 2018.
World J Gastroenterol. Jul 28, 2018; 24(28): 3181-3191
Published online Jul 28, 2018. doi: 10.3748/wjg.v24.i28.3181
Published online Jul 28, 2018. doi: 10.3748/wjg.v24.i28.3181
Figure 1 Literature search process for the systematic review and meta-analysis.
HCV: Hepatitis C virus; HIV: Human immunodeficiency virus.
Figure 2 Hepatitis B virus reactivation in hepatitis C virus patients with chronic hepatitis B virus infection.
Pooled estimates of hepatitis B virus reactivation in hepatitis C virus patients with chronic hepatitis B surface antigen-positive hepatitis B virus infection.
Figure 3 Hepatitis B virus reactivation according to baseline hepatitis B virus DNA level in hepatitis C virus patients with chronic hepatitis B virus infection.
Relative risk of hepatitis B virus (HBV) reactivation according to baseline HBV DNA level in hepatitis C virus patients with chronic hepatitis B surface antigen-positive HBV infection.
Figure 4 Funnel plot of 26 studies estimating the hepatitis B virus reactivation rates in hepatitis C virus patients with chronic hepatitis B virus infection.
The vertical line corresponds to the summary hepatitis B virus reactivation rates as estimated from the random effect model. The publication bias is presented; P = 0.03, as tested by Egger’s test.
Figure 5 Hepatitis B virus reactivation in hepatitis C virus patients with previous hepatitis B virus infection.
Pooled estimates of hepatitis B virus (HBV) reactivation in hepatitis C virus patients with previous hepatitis B surface antigen-negative but HBcAb-positive HBV infection.
Figure 6 Hepatitis B virus reactivation-related hepatitis in hepatitis C virus patients with chronic hepatitis B virus infection.
Overall risk of hepatitis B virus (HBV) reactivation-related hepatitis in hepatitis C virus patients with chronic hepatitis B surface antigen-positive HBV infection.
Figure 7 Hepatitis B virus reactivation-related hepatitis according to baseline hepatitis B virus DNA level.
Relative risk of hepatitis B virus (HBV) reactivation-related hepatitis according to baseline HBV DNA level in hepatitis C virus patients with chronic hepatitis B surface antigen-positive HBV infection.
Figure 8 Hepatitis B virus reactivation in hepatitis B surface antigen-positive patients with and without antiviral prophylaxis.
Relative risk of hepatitis B virus reactivation in hepatitis B surface antigen-positive patients with antiviral prophylaxis and without prophylaxis. HBV: Hepatitis B virus.
- Citation: Jiang XW, Ye JZ, Li YT, Li LJ. Hepatitis B reactivation in patients receiving direct-acting antiviral therapy or interferon-based therapy for hepatitis C: A systematic review and meta-analysis. World J Gastroenterol 2018; 24(28): 3181-3191
- URL: https://www.wjgnet.com/1007-9327/full/v24/i28/3181.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i28.3181