Multiple cytokine profiling in serum for early detection of gastric cancer

doi:10.3748/wjg.v24.i21.2269

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2018; 24(21): 2269-2278
Published online Jun 7, 2018. doi: 10.3748/wjg.v24.i21.2269

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Figure 1 Comparison of carcinoembryonic antigen, CA724, IL-6, IL-8 and TNF-α in the three groups. A: IL-6; B: IL-8; C: TNF-α; D: CEA; E: CA724. CA: Cancer antigen; CEA: Carcinoembryonic antigen.

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Figure 2 Diagnostic value of IL-6, IL-8, TNF-α and CA724 for discriminating the atypical hyperplasia group and gastric cancer group. A: IL-6; B: IL-8; C: TNF-α; D: CA724. CA: Cancer antigen; CEA: Carcinoembryonic antigen.

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Figure 3 Joint analysis of CEA, CA724, IL-6, IL-8 and TNF-α for discriminating the healthy control group and gastric cancer group. A: Healthy control group vs gastric cancer group; B: Healthy control group vs early stage gastric cancer group; C: Healthy control group vs advanced stage gastric cancer group. CA: Cancer antigen; CEA: Carcinoembryonic antigen.

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Figure 4 Joint analysis of IL-6, IL-8, TNF-α and CA724 for discriminating the atypical hyperplasia group and gastric cancer group. A: Atypical hyperplasia group vs gastric cancer group; B: Atypical hyperplasia group vs early stage gastric cancer group; C: Atypical hyperplasia group vs advanced stage gastric cancer group. CA: Cancer antigen; CEA: Carcinoembryonic antigen.

Citation: Li J, Xu L, Run ZC, Feng W, Liu W, Zhang PJ, Li Z. Multiple cytokine profiling in serum for early detection of gastric cancer. World J Gastroenterol 2018; 24(21): 2269-2278
URL: https://www.wjgnet.com/1007-9327/full/v24/i21/2269.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i21.2269