Predictive and prognostic value of serum AFP level and its dynamic changes in advanced gastric cancer patients with elevated serum AFP

Figure 1 The receiver operating characteristic curve analysis for predictive value of serum alpha-fetoprotein level. The area under the curve is 0.670.

Figure 2 Changes of serum alpha-fetoprotein levels at the time of diagnosis, evaluation, and progression. A: Dynamic changes of serum AFP in patients whose AFP declined by ≥ 50% when evaluated as PR; B: Dynamic changes of serum AFP in patients whose AFP declined by < 50% when evaluated as PR. PR: Partial response; PD: Progressive disease.

Figure 3 The median overall survival of patients with liver metastasis and those without was 16. 7 m and 12.0 m, respectively (P = 0.048).

Figure 4 The median overall survival of patients with a ≥ 50% serum alpha-fetoprotein level decline and those with a < 50% decline was 17. 5 mo and 10.0 mo, respectively (P = 0.003).